ANNEX 2
ABBREVIATIONS USED IN THE MONOGRAPHS
ADI acceptable daily intake
ALAT alanine aminotransferase
ALP alkaline phosphatase
ASAT aspartate aminotransferase
ATP adenosine triphosphate
AUC area under the curve
BUN blood urea nitrogen
bw body weight
CHO Chinese hamster ovary
CMC carboxymethyl cellulose
CNS central nervous system
DMSO dimethyl sulfoxide
DNA deoxyribonucleic acid
ECG electrocardiogram
ED50 effective dose, median
F female
F1 filial generation, first
F2 filial generation, second
FAO Food and Agriculture Organization of the
United Nations
g gram
GABA gamma-aminobutyric acid
GC gas chromatography
GI gastrointestinal
GOT glutamate-oxalate transaminase
GPT glutamate-pyruvate transaminase
GSH glutathione
h hour
Hb haemoglobin
HDL high density lipoprotein
HPLC high performance liquid chromatography
i.m. intramuscular
i.p. intraperitoneal
i.v. intravenous
IARC International Agency for Research on Cancer
IPCS International Programme on Chemical Safety
JECFA Joint FAO/WHO Expert Committee on Food
Additives
kg kilogram
l litre
LC50 lethal concentration, median
LD50 lethal dose, median
LDH lactate dehydrogenase
M male
mg milligram
MIC minimum inhibitory concentration
ml millilitre
MTD maximum tolerated dose
NADPH nicotinamide adenine dinucleotide phosphate
(reduced)
NOEL no-observed-effect level
p.o. per os (by mouth)
PCV packed cell volume
RBC red blood cell count
s.c. subcutaneous
SCE sister chromatid exchange
SGOT serum glutamate-oxalate-transaminase
SGPT serum glutamate-pyruvate-transaminase
t1/2 half-reaction time
TSH thyroid stimulating hormone
UDS unscheduled DNA synthesis
WBC white blood cell
WHO World Health Organization