FAO Nutrition Meetings
Resort Series No. 44A
WHO/Food Add./68.33
TOXICOLOGICAL EVALUATION OF SOME
FLAVOURING SUBSTANCES AND
NON-NUTRITIVE SWEETENING AGENTS
Geneva, 21-28 August 1967
The Eleventh Report of the Joint FAO/WHO Expert Committee on Food
Additives is published as FAO Nutrition Meetings Report Series,
1967, No. 44; Wld Hlth Org. techn. Rep. Ser., 1968, 383. This
Report contains general considerations, including the principles
adopted for the evaluation, and a summary of the results of the
evaluations of a number of food additives. Additional information,
such as biological data and a toxicological evaluation, considered at
that meeting, is to be found in this document.
Food and Agriculture Organization of the United Nations
World Health Organization
1967
NONANAL
Synonyms Pelargonic aldehyde; Aldehyde C-9
Chemical name Nonanal
Empirical formula C9H18O
Structural formula CH3(CH2)7CHO
Molecular weight 142.24
Definition Nonanal contains not less than 92 per cent.
C9H18O.
Description A colourless to light yellow liquid having a
strong fatty odour which develops an orange
and rose character on being diluted.
Biological Data
Biochemical aspects
No information available.
Acute toxicity
None available.
Short-term studies
Rat. In a 12-week feeding study on 15 males and 15 females,
using mixed aldehydes, no adverse effects were seen at 25.6 mg/kg
body-weight/day (Oser, 1967).
Long-term studies
None available.
Comments
The evaluation is based on the short-term studies. Metabolic
studies are needed.
EVALUATION
Estimate of acceptable daily intake for man
mg/kg body-weight
Conditional acceptance 0-0.1
Further work required
Biochemical studies in animals and man.
REFERENCES
Oser, B. L. (1967) Unpublished report