ANNEX II ACCEPTABLE DAILY INTAKES, RESIDUE LIMITS AND GUIDELINE LEVELS PROPOSED AT THE 1986 MEETING These figures are additional to, or amend, those recorded in Annexes of the reports of earlier meetings. Limits recommended at meetings from 1965 to 1977 inclusive are summarized in document FAO/WHO 1978c. This table includes maximum acceptable daily intakes (ADIs), maximum residue limits (MRLs) and guideline levels (GLs). These terms are defined in Annex III of the report of the 1975 meeting. Part I lists ADIs and MRLs. Part 2 lists GLs. Some ADIs are temporary: this is indicated either by the word "Temporary" or by the year of expiry in parenthesis below the ADI. All MRLs for compounds with temporary ADIs are necessarily temporary. MRLs may also be temporary, irrespective of the status of the ADI, because additional information is required for the evaluation of residues. These are followed by the qualification (TMRL). If an MRL is an amendment, the previous value is also recorded, together with the year in which the level was estimated. The absence of a figure in the "Previous" column indicates that the recommendation is the first for the commodity or group concerned. The table includes the Codex Classification Numbers (CCNs) of both the compounds and the commodities listed, to facilitate reference to the Guide to Codex Maximum Limits for Pesticide Residues. CCNs for commodities are those of the revised Classification. As stated in section 2.9 (q.v.), commodities are listed in the order of the "Types" in the Classification, and within each Type in alphabetical order. Different Types are not differentiated by sub-headings, but are separated from one another by spaces. The Types are listed in the following order: Type Code Fruits 01 Vegetables 02 Grasses 03 Nuts and seeds 04 Herbs and spices 05 Mammalian products 06 Poultry products 07 Primary animal feed commodities of plant origin 11 Secondary food commodities of plant origin 12 Derived products of plant origin 13 PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) AMITRAZ 0.003 OC 0691 Cotton seed oil, 0.05 0.05 for (122) crude cotton seed 1980, 1983 oil (1980) 1984, 1985 Residue: sum of amitraz (calculated as N-(2,4-dimethylphenyl)-N'- methylformamidine) and N-(2,4-dimethylphenyl)-N'- methylformamidine) Remarks: clarification of commodity description CARBOSULFAN 0.01 (145) 1984 Remarks: TADI replaced by ADI at higher level. TMRLs replaced by MRLs. CHLORDANE 0.0005 (012) 1965, 1967, 1969, 1970, 1972, 1974, 1977, 1982, 1984 Remarks: TADI replaced by ADI at lower level. TMRLs replaced by MRLs. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) CHLORDIMEFORM 0.0001 (013) (1987) 1971, 1975, 1977, 1978, 1979, 1980, 1985 Residue: sum of chlordimeform and its metabolites hydrolysable to 4-chloro-o-toluidine, determined as 4-chloro-o-toluidine and expressed as chlordimeform. Remarks: note changed definition of residue. CLOFENTEZINE 0.02 FC 0001 Citrus fruits 0.5 (TMRL) - (156) FP 0009 Pome fruits 0.5 - FS 0012 Stone fruits 0.2 (TMRL) - FB 0275 Strawberry 2 (TMRL) - VC 0424 Cucumber 1 (TMRL) - PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) CLOFENTEZINE MM 0812 Cattle meat 0.01* (TMRL) - (cont.) MO 0812 Cattle, edible offal of 0.1 (TMRL) - ML 0812 Cattle milk 0.01* (TMRL) - Residue: clofentezine CYHALOTHRIN 0.02 FP 0009 Pome fruits 0.2 0.5 (1984) (146) 1984 VB 0041 Cabbages, head 0.2 - VR 0589 Potato 0.02* - SO 0691 Cotton seed 0.02* - OC 0691 Cotton seed oil, crude 0.02* - OR 0691 Cotton seed oil, edible 0.02* - Residue: cyhalothrin (sum of all isomers) PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) CYPERMETHRIN 0.05 MO 0105 Edible offal (118) (Mammalian) 0.05* 0.2 (1981) 1979, 1981, 1982, ML 0106 Milks 0.05 0.01 for milk 1984, 1985 (1981) Residue: cypermethrin (sum of isomers) 2, 4-D 0.3 GC 0645 Maize 0.02* ) 0.2 (1980) (020) GC 0649 Rice 0.02* ) for cereals 1970, 1971, 1974, GC 0651 Sorghum 0.02* ) except 1975, 1980, 1985 barley, maize, oats & wheat Residue: 2, 4-D DELTAMETHRIN 0.01 SB 0716 Coffee beans 2 0.02 (1985) (135) 1980, 1981, 1982, 1984, 1985 Residue: deltamethrin Remarks: The increased MRL is to accommodate post-harvest use on the stored product. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) DIMETHOATE 0.002 FI 0327 Banana 1 ) - (027) (1987) ) 1965, 1966, 1967, VP 0061 Beans, except 2 ) 1970, 1977, 1983, broad bean and ) 1984 soya bean ) VR 0574 Beetroot 0.2 ) VB 0400 Broccoli 2 ) VB 0402 Brussels sprouts 2 ) VB 0041 Cabbages, head 2 ) VR 0577 Carrot 1 ) VB 0404 Cauliflower 2 ) 2 for vegetables VS 0624 Celery 1 ) (not otherwise VC 0424 Cucumber 2 ) listed) (1967) VL 0480 Kale 0.5 ) VL 0482 Lettuce, head 2 ) VL 0483 Lettuce, leaf 2 ) VA 0385 Onion, bulb 0.2 ) PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) DIMETHOATE VP 0063 Peas 0.5 ) (cont.) VL 0502 Spinach 1 ) VR 0506 Turnip 0.5 ) VS 0469 Witloof chicory 0.5 ) (sprouts) ) Residue: dimethoate Remarks: Note changed definition of residue. The previous recommendation for "vegetables (not otherwise listed)" is withdrawn. Recommendations for other individual fruits and vegetables confirmed. The recommendation for bananas covers post-harvest use. ETHION 0.006 (034) (Temporary) 1968, 1969, 1970, 1972, 1975, 1982, 1983, 1985 Remarks: TADI extended at higher level. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) ETHYLENETHIOUREA 0.002 (108) (Temporary) 1974, 1977 Residue: ethylenethiourea Remarks: as a TADI has been estimated, existing guideline levels are replaced by TMRLs. ETRIMFOS 0.003 (123) 1980, 1982 Residue: sum of etrimfos, its oxygen analogue and 6-ethoxy-2-ethyl-4-hydroxypyrimidine Remarks: Note changed definition of residue. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) FENITROTHION 0.003 FC 0001 Citrus fruits 2 - (037) 1969, 1974, 1976, 1977, 1979, 1982, 1983, 1984 Residue: fenitrothion Remarks: TADI replaced by ADI at same level. TMRLs replaced by MRLs. MRL replaces 2 mg/kg for oranges and mandarins. FENTIN 0.0005 (040) 1965, 1970, 1972 Residue: fentin, excluding inorganic tin and di- and mono- phenyltin Remarks: Note changed definition of residue. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) FENVALERATE 0.02 VB 0400 Broccoli 2 ) (119) VB 0402 Brussels sprouts 2 ) 2 for "Brassica 1979, 1981, 1982, VB 0404 Cauliflower 2 ) leafy vegetables 1984, 1985 VL 0466 Chinese cabbage, ) (except headed type "Pak-choi" 1 ) cabbage)" (1984) VL 0480 Kale (collards) 10 ) Residue: fenvalerate Remarks: Temporary ADI replaced by ADI at same level. TMRLs replaced by MRLs. Commodity descriptions for beans and peas clarified. Limits for meat (in the fat) and milk confirmed. FOLPET 0.01 (041) (Temporary) 1969, 1973, 1974, 1982, 1984 Remarks: As a TADI has been estimated, existing GLs are replaced by TMRLs. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) GLYPHOSATE 0.3 VD 0071 Beans (dry) 2 - (157) VD 0072 Peas (dry) 5 - VP 0541 Soya bean (immature seeds) 0.2 - VO 0447 Sweet corn (corn-on-the-cob) 0.05* GC 0640 Barley 20 - GC 0645 Maize 0.05* - GC 0647 Oats 20 - GC 0649 Rice 0.05* - GC 0651 Sorghum 0.05* - GC 0654 Wheat 20 - SO 0691 Cotton seed 0.5 - SO 0495 Rape seed 10 - MO 0812 Cattle, edible offal of 2 - MM 0812 Cattle meat 0.05* - ML 0812 Cattle milk 0.05* - MM 0818 Pig meat 0.05* - MO 0818 Pig, edible offal of 1 - PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) GLYPHOSATE PE 0112 Eggs (poultry) 0.05* - (cont.) PM 0110 Poultry meat 0.05* - AS 0162 Hay or fodder (dry) of grasses 50 - AS 0081 Straw & fodder (dry) of cereal grains 100 - Residue: glyphosate IMAZALIL 0.01 (110) 1977, 1980, 1984, 1985 Remarks: TADI replaced by ADI at same level. TMRLs replace by MRLs. ISOFENPHOS 0.001 FC 0001 Citrus fruits 2 1 (1982) (131) 1981, 1982, 1984, 1985 Residue: sum of isofenphos and its oxygen analogue Remarks: TADI replaced by ADI at higher level. TMRLs replaced by MRLs. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) MECARBAM 0.002 MM 0812 Cattle meat 0.005* - (124) MO 0812 Cattle, 1980, 1983, 1985 edible offal of 0.005* - ML 0812 Cattle milk 0.01 - Residue: mecarbam Remarks: TADI replaced by ADI at higher level. TMRLs replaced by MRLs. METALAXYL 0.03 FI 0326 Avocado 2 0.05* (1985) (138) 1982, 1984, 1985 VO 0051 Peppers 1 - VL 0502 Spinach 5 1 (1982) Residue: sum of metalaxyl and its metabolites containing the 2,6-dimethylaniline moiety, determined as 2,6-dimethylaniline and calculated and expressed as metalaxyl. Remarks: Note changed definition of residue. Changes in limits for avocados and spinach result from new usage and residue data as well as the change in residue definition. All MRLs no longer temporary. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) METHACRIFOS 0.0003 (125) (Temporary) 1980, 1982 Remarks: TADI extended at same level. METHIOCARB 0.001 (132) 1981, 1983, 1984, 1985 Residue: sum of methiocarb, its sulphoxide and its sulphone Remarks: 0.05 mg/kg confirmed as the practical lower limit of determination. METHOMYL 0.01 (094) (Temporary) 1975, 1976, 1977, 1978 Residue: methomyl Remarks: As a TADI has been estimated, existing GLs are replaced by TMRLs. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) METHOPRENE 0.06 VO 0450 Mushrooms 0.2 1 (1984) (147) (Temporary) 1984 ML 0812 Cattle milk 0.05 0.002 (1984) Residue: methoprene OMETHOATE 0.0003 FI 0341 Kiwi fruit MRL withdrawn 2 (1984) (055) 1971, 1975, 1978, VS 0620 Artichoke 0.5 ) 1979, 1981, 1984, VP 0061 Beans, except ) 1985 broad bean and ) soya bean 0.2 ) VB 0400 Broccoli 0.2 ) VB 0402 Brussels sprouts 0.2 ) VB 0041 Cabbages, head 0.2 ) 2 for vegetables VR 0577 Carrot 0.05 ) (not otherwise VB 0404 Cauliflower 0.2 ) listed) (1975, VS 0624 Celery 0.1 ) when existing VC 0424 Cucumber 0.2 ) TMRLs were deleted VL 0480 Kale 0.2 ) and replaced by VL 0482 Lettuce, head 0.2 ) limits for dimethoate). PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) OMETHOATE VL 0483 Lettuce, leaf 0.2 ) (cont.) VA 0385 Onion, bulb 0.1 ) VP 0063 Peas 0.1 ) VL 0502 Spinach 0.1 ) VR 0506 Turnip 0.2 ) VS 0469 Witloof chicory 0.5 ) (sprouts) Vegetables (not otherwise listed) MRL withdrawn 2 (1975) GC 0080 Cereal grains 0.05 - Residue: omethoate Remarks: The MRL for Kiwi fruit is withdrawn as the use is not yet registered. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) OXAMYL 0.03 VD 0526 Beans, kidney MRL withdrawn 0.05* (1985) (126) (dry) 1980, 1983, 1984, VP 0061 Beans, except 5 - 1985 broad bean and soya bean Residue: sum of oxamyl and its oxime, expressed as oxamyl Remarks: recommendation for beans, except broad bean and soya bean replaces recommendations for beans, kidney and beans, Lima at the same level. PARAQUAT 0.004 (057) as 1970, 1972, 1976, paraquat 1978, 1981, 1982, cation 1985 Remarks: TADI replaced by ADI at higher level. TMRLs replaced by MRLs. Max. ADI is equal to 0.006 mg/kg bw as paraquat dichloride. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) PERMETHRIN 0.05 MM 0095 Meat (from (120) for 40%-cis, mammals other than 1979, 1980, 1981, 60%-trans marine mammals) 1 (in the fat) - 1982, 1983, 1984, material MO 0105 Edible offal 1985 only (mammalian) 0.1 - Residue: permethrin (sum of isomers) Remarks: limits (unchanged in value) replace those estimated in 1980 for meat (in the fat) and edible offal of cattle, pigs and sheep. PHOSMET 0.02 VP 0063 Peas 0.2 ) 0.1 mg/kg for peas (103) VD 0072 Peas (dry) 0.02 ) (fresh or dried) 1978 1976, 1977 VO 0447 Sweet corn (correction to (corn-on-the-cob) 0.5 ) 0.2 mg/kg for maize 1976 Evaluations) ) (kernel & cobs with 1978, 1979, 1981, GC 0645 Maize 0.5 ) husks removed) 1978 1984, 1985 AL 1020 Alfalfa fodder 40 ) 20 mg/kg for alfalfa AL 1021 Alfalfa forage ) (dry) 1984 (green) 40 ) AL 0072 Pea hay or pea fodder (dry) 10 ) PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) PHOSMET AL 0528 Peas vines 5 mg/kg for forage (cont.) (green) 10 ) crops (dry) (except AS 0645 Maize fodder 10 ) alfalfa) 1984 AF 0645 Maize forage 10 ) Residue: sum of phosmet and its oxygen analogue PHOSPHAMIDON 0.0005 (061) 1965, 1966, 1968, 1969, 1972, 1974, 1982, 1985 Remarks: TADI replaced by ADI at same level. TMRLs replaced by MRLs. PROPAMOCARB 0.1 VB 0402 Brussels sprouts 1 - (148) VB 0041 Cabbages, head 0.1 - 1984 VS 0624 Celery 0.2 - VL 0482 Lettuce, head 10 - VR 0494 Radish 5 - Residue: propamocarb (base) Remarks: TADI replaced by ADI at higher level. TMRLs replaced by MRLs. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) THIODICARB 0.03 (154) 1985 Remarks: TADI replaced by ADI at higher level. TMRLs replaced by MRLs. TRIADIMEFON 0.03 FI 0353 Pineapple 3 2 (1983) (133) 1979, 1981, 1983, VD 0524 Chick-pea (dry) 0.1* - 1984, 1985 VC 0045 Fruiting vegetables, cucurbits 0.2 - VA 0387 Onion, Welsh 0.1* - AV 0596 Sugar beet leaves or tops 2 0.1* (1979) Residue: sum of triadimefon and triadimenol Remarks: the recommendation for fruiting vegetables, cucurbits replaces previous recommendations for cucumbers, melons and pumpkins at levels of 0.2, 0.5 and 0.1* mg/kg respectively. PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) TRIAZOPHOS 0.0002 FI 0327 Banana 1 2 (1983) (143) (Temporary) 1982, 1983, 1984 VA 0385 Onion, bulb 0.05* 0.1 (1983) (corrections to 1983 report) Residue: triazophos Remarks: TADI extended at same level. VINCLOZOLIN 0.04 FB 0264 Blackberries 5 - (158) (Temporary) FS 0013 Cherries 3 - FB 0021 Currants, black, red, white 5 - FB 0266 Dewberries (including Boysenberry and Loganberry) 5 FB 0268 Gooseberry 5 - FB 0269 Grapes 5 - FI 0341 Kiwi fruit 10 - FS 0247 Peach 2 - PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) VINCLOZOLIN FP 0009 Pome fruits 1 - (cont.) FB 0272 Raspberries, - red, black 5 - FB 0275 Strawberry 10 - VB 0041 Cabbages, head 1 - VP 0526 Common bean 2 - VB 0404 Cauliflower 1 - VR 0469 Chicory, roots (after forcing) 5 - VC 0424 Cucumber 1 - VP 0529 Garden pea, shelled succulent seeds 1 VC 0425 Gherkin 1 - VL 0482 Lettuce, Head 5 - VC 0046 Melons, except watermelon 1 - VA 0385 Onion, bulb 1 - VO 0445 Peppers, Sweet 2 - VR 0589 Potato 0.1 - PART 1 - ACCEPTABLE DAILY INTAKES (ADIs) AND MAXIMUM RESIDUE LIMITS (MRLs) (cont.) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) VINCLOZOLIN VO 0448 Tomato 3 - (cont.) VS 0469 Witloof chicory (sprouts) 2 - MM 0812 Cattle meat 0.05* - ML 0812 Cattle milk 0.05* - PE 0840 Chicken eggs 0.05* - PM 0840 Chicken meat 0.05* - Residue: sum of vinclozolin and all metabolites containing 3,5-dichloroaniline, expressed as vinclozolin PART 2 - GUIDELINE LEVELS (NO ACCEPTABLE DAILY INTAKES) Pesticide Recommended Commodity Recommended MRL (mg/kg) (CCN) maximum Year(s) of ADI CCN Name New Previous previous (mg/kg bw) evaluation(s) BENALAXYL FB 0269 Grapes 0.5 - (155) VC 0424 Cucumber 0.05 - VC 0046 Melons, except watermelon 0.1 - VA 0385 Onion, bulb 0.2 - VO 0445 Peppers, sweet 0.05 - VR 0589 Potato 0.01* - VO 0448 Tomato 0.5 - DH 1100 Hops, dry 0.2 - Residue: benalaxyl
See Also: Toxicological Abbreviations