International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 3 (1973) (p. 201)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Dibenzo(a,e)pyrene has produced tumours in mice following skin paintings and s.c. injection. In skin painting experiments, dibenzo(a,e)pyrene was less active than benzo(a)pyrene. It has not been tested by other routes in the mouse or in other species.

5.2 Human carcinogenicity data

No case reports or epidemiological studies on the significance of dibenzo(a,e)pyrene exposure to man are available. The only reported occurrence of this substance was in the exhaust of internal combustion engines.

Subsequent evaluations: Vol. 32 (1983); Suppl. 7 (1987) (p. 62: Group 2B)

For definition of Groups, see Preamble Evaluation.

Last updated: 16 March 1998

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       Toxicological Abbreviations