Sterigmatocystin (IARC Summary & Evaluation, Volume 10, 1976)

International Agency for Research on Cancer (IARC) - Summaries & Evaluations

STERIGMATOCYSTIN

VOL.: 10 (1976) (p. 245)

CAS No.: 10048-13-2
Chem. Abstr. Name: 3a,12c-Dihydro-8-hydroxy-6-methoxy-7H-furo-[3',2':4,5]furo-
[2,3-c]xanthen-7-one

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Sterigmatocystin is carcinogenic in mice and rats following its oral administration; it produced lung tumours in mice and liver tumours in rats. In rats, it also produced skin and liver tumours following its application to the skin and sarcomas at the site of its subcutaneous injection.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Previous evaluation: Vol. 1 (1972)

Subsequent evaluation: Suppl. 7 (1987) (p. 72: Group 2B)

For definition of Groups, see Preamble Evaluation.

Last updated 12/4/1997





























    See Also:
       Toxicological Abbreviations
       Sterigmatocystin (IARC Summary & Evaluation, Volume 1, 1972)