International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 12 (1976) (p. 121)

CAS No.: 14484-64-1
Chem. Abstr. Name: Tris(dimethylcarbamodithioato-S,S')iron

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Ferbam has been tested by oral administration in mice and rats and by single subcutaneous injection in mice. Although no carcinogenic effect was observed in these tests, the available data are insufficient for an evaluation of the carcinogenicity of this compound to be made.

Ferbam can react with nitrite under mildly acid conditions, simulating those in the human stomach, to form N-nitrosodimethylamine, which has been shown to be carcinogenic in seven animal species (IARC, 1972).

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 63: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 25 March 1998

    See Also:
       Toxicological Abbreviations
       Ferbam (ICSC)
       Ferbam (FAO Meeting Report PL/1965/10/1)
       Ferbam (FAO/PL:1967/M/11/1)
       Ferbam (Pesticide residues in food: 1996 evaluations Part II Toxicological)