International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 12 (1976) (p. 137)

CAS No.: 12427-38-2
Chem. Abstr. Name: {[1,2-Ethanediylbis(carbamodithioato)](2-)}-manganese

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Maneb has been tested in mice and rats by oral administration and by single subcutaneous injection. Its oral administration produced an increased incidence of lung tumours in mice of one strain, but no increase was observed in three other strains. The studies in rats cannot be evaluated due to the small numbers of surviving animals. No evaluation of the carcinogenicity of this compound can be made.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 65: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 25 March 1998

    See Also:
       Toxicological Abbreviations
       Maneb (ICSC)
       Maneb (FAO Meeting Report PL/1965/10/1)
       Maneb (FAO/PL:1967/M/11/1)
       Maneb (Pesticide residues in food: 1993 evaluations Part II Toxicology)