VOL.: 29 (1982) (p. 83)
There is no clear evidence that benzoyl chloride is mutagenic in bacterial systems; it was negative in a rec-assay with Bacillus subtilis.
No data were available to assess the teratogenicity of this compound to experimental animals.
No data were available to assess the mutagenicity or teratogenicity of this compound to man.
No case report or epidemiological study involving exposure to benzoyl chloride alone was available to the Working Group. Six cases of respiratory cancer have been reported among benzoyl chloride production workers in two small plants. The cases occurred in young workers, three of whom were nonsmokers.
Although the epidemiological data were inadequate to evaluate the carcinogenicity of benzoyl chloride alone, they provide limited evidence that employment in the production of benzoyl chloride and its chlorinated toluene derivatives represents a carcinogenic risk to man.
No evaluation could be made on the carcinogenicity to man of benzoyl chloride itself.
For definition of the italicized terms, see Preamble Evaluation.
Subsequent evaluation: Suppl. 7 (1987); Vol. 71 (1999)
See Also: Toxicological Abbreviations Benzoyl chloride (ICSC) Benzoyl Chloride (IARC Summary & Evaluation, Supplement7, 1987)