ICSC 0224 - BENZIDINE

BENZIDINE	ICSC: 0224 (November 2009)
(1,1'-Biphenyl)-4,4'-diamine 4,4'-Diaminobiphenyl p-Diaminodiphenyl Biphenyl-4,4'-ylenediamine

CAS #: 92-87-5

UN #: 1885

EC Number: 202-199-1

	ACUTE HAZARDS	PREVENTION	FIRE FIGHTING
FIRE & EXPLOSION	Combustible. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Use water spray, foam, powder, carbon dioxide.

See EFFECTS OF LONG-TERM OR REPEATED EXPOSURE. AVOID ALL CONTACT!
	SYMPTOMS	PREVENTION	FIRST AID
Inhalation		Use closed system and ventilation.	Fresh air, rest.
Skin	MAY BE ABSORBED!	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Wear protective gloves when administering first aid.
Eyes		Wear face shield or eye protection in combination with breathing protection if powder.	Rinse with plenty of water (remove contact lenses if easily possible).
Ingestion		Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth.

SPILLAGE DISPOSAL	CLASSIFICATION & LABELLING
Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.	According to UN GHS Criteria DANGER Harmful if swallowed Suspected of causing genetic defects May cause cancer Very toxic to aquatic life with long lasting effects Transportation UN Classification UN Hazard Class: 6.1; UN Pack Group: II
STORAGE
Provision to contain effluent from fire extinguishing. Separated from strong oxidants and food and feedstuffs. Keep in the dark. Well closed. Store in an area without drain or sewer access.
PACKAGING
Unbreakable packaging. Put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs.

BENZIDINE

ICSC: 0224

PHYSICAL & CHEMICAL INFORMATION
Physical State; Appearance COLOURLESS OR REDDISH CRYSTALLINE POWDER. TURNS DARK ON EXPOSURE TO AIR AND LIGHT. Physical dangers No data. Chemical dangers Decomposes on heating and on burning. This produces toxic fumes including nitrogen oxides. Reacts violently with strong oxidants, especially nitric acid.	Formula: C₁₂H₁₂N₂ / NH₂C₆H₄-C₆H₄NH₂ Molecular mass: 184.2 Boiling point: 401°C Melting point: 120°C Density: 1.3 g/cm³ Solubility in water, g/100ml at 25°C: <0.05 (very poor) Relative vapour density (air = 1): 6.4 Octanol/water partition coefficient as log Pow: 1.34

PHYSICAL & CHEMICAL INFORMATION

Physical State; Appearance
COLOURLESS OR REDDISH CRYSTALLINE POWDER. TURNS DARK ON EXPOSURE TO AIR AND LIGHT.

Physical dangers
No data.

Chemical dangers
Decomposes on heating and on burning. This produces toxic fumes including nitrogen oxides. Reacts violently with strong oxidants, especially nitric acid.

Formula: C₁₂H₁₂N₂ / NH₂C₆H₄-C₆H₄NH₂
Molecular mass: 184.2
Boiling point: 401°C
Melting point: 120°C
Density: 1.3 g/cm³
Solubility in water, g/100ml at 25°C: <0.05 (very poor)
Relative vapour density (air = 1): 6.4
Octanol/water partition coefficient as log Pow: 1.34

EXPOSURE & HEALTH EFFECTS
Routes of exposure The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. Effects of short-term exposure	Inhalation risk Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered. Effects of long-term or repeated exposure This substance is carcinogenic to humans.

EXPOSURE & HEALTH EFFECTS

Routes of exposure
The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion.

Effects of short-term exposure

Inhalation risk
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed, especially if powdered.

Effects of long-term or repeated exposure
This substance is carcinogenic to humans.

OCCUPATIONAL EXPOSURE LIMITS
TLV: A1 (confirmed human carcinogen); (skin). MAK: carcinogen category: 1. MAK skin absorption (H)

ENVIRONMENT
The substance is very toxic to aquatic organisms. It is strongly advised not to let the chemical enter into the environment.

NOTES
Do NOT take working clothes home. TLV Note: Exposure by all routes should be carefully controlled to levels as low as possible.

ADDITIONAL INFORMATION

EC Classification
Symbol: T, N; R: 45-22-50/53; S: 53-45-60-61; Note: E

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    See Also:
       Toxicological Abbreviations
       Benzidine  (IARC Summary & Evaluation, Supplement7, 1987)
       Benzidine (IARC Summary & Evaluation, Volume 1, 1972)