| NEOMYCIN | |
| Chemical names: | D-STREPTAMINE, O-2,6-DIAMINO-2,6-DIDEOXY-alpha-D-GLUCOPYRANOSYL-(1?>4)-O-[O-2,6- DIAMINO-2,6-DIDEOXY-beta-L-IDOPYRANOSYL-(1?>3)-beta-D-RIBOFURANOSYL-(1?>5)]-2- DEOXY-, SULFATE (1:1) (SALT) | Functional class: | VETERINARY DRUG (ANTIMICROBIAL AGENT) | Latest evaluation: | 2003 | ADI: | 0-0.06 mg/kg bw | Comments/MRLs: | MRLs (expressed as parent drug): Liver (cattle): 0.5 mg/kg; Kidney (cattle): 10 mg/kg; Milk (cattle): 1.5 mg/kg. The MRLs of 0.5 mg/kg for cattle muscle and fat and MRLs for tissues of other species recommended at the forty-seventh meeting (1996) were maintained. | Report: | TRS 918-JECFA 60/5 | Residues: | FNP 41/15-JECFA 60/53 | Tox monograph: | FAS 51-JECFA 60/3 | Previous status: | 2002, TRS 911-JECFA 58/32, FNP 41/12-JECFA 52/91 (1999), FAS 38-JECFA 47/79 (1996). 0-0.06 mg/kg bw (1996). THE COMMITTEE MAINTAINED THE MRLs RECOMMENDED AT ITS FIFTY-SECOND MEETING (1999) AND DECIDED TO RECONSIDER THEM AT A SUBSEQUENT MEETING, WHEN IT WOULD MAKE ANY NECESSARY CHANGES IN THE ADI.
1999, TRS 893-JECFA 52/25, FNP 41/12-JECFA 52/91, FAS 38-JECFA 47/79 (1996). 0-0.06 mg/kg bw (1996). MRLs (EXPRESSED AS PARENT DRUG): MUSCLE AND FAT (CATTLE, SHEEP, PIGS, GOATS, TURKEYS, DUCKS AND CHICKENS): 0.5 mg/kg; LIVER (CATTLE): 15 mg/kg; KIDNEY (CATTLE): 20 mg/kg; LIVER AND KIDNEY (SHEEP, PIGS, GOATS, TURKEYS, DUCKS AND CHICKENS): 0.5 mg/kg; MILK (CATTLE): 0.5 mg/l; EGGS (CHICKEN): 0.5 mg/kg. THE MRLs FOR THE LIVER AND KIDNEY OF CATTLE WERE RECOMMENDED AT THE FIFTY-SECOND MEETING (1999); MRLs FOR THE KIDNEY IN SHEEP, PIGS, GOATS, TURKEYS, DUCKS AND CHICKENS WERE RECOMMENDED AT THE FORTY-SEVENTH MEETING (1996); ALL REMAINING MRLs WERE RECOMMENDED AT THE FORTY-THIRD MEETING (1994). FU. MRL 1996, TRS 876-JECFA 47/25, FNP 41/9-JECFA 47/73, FAS 38-JECFA 47/79. 0-0.06 mg/kg bw. MRLs (EXPRESSED AS PARENT DRUG): MUSCLE, LIVER AND FAT (CATTLE, SHEEP, PIGS, GOATS, TURKEYS, DUCKS AND CHICKENS), EGGS (CHICKENS), MILK (CATTLE): 0.5; KIDNEY (CATTLE, SHEEP, PIGS, GOATS, TURKEYS, DUCKS AND CHICKENS): 10. FU. MRL 1994, TRS 855-JECFA 43/31, FNP 41/7-JECFA 43/57, FAS 34-JECFA 43/113. 0-0.03 (TEMPORARY). MRLs (TEMPORARY) (EXPRESSED AS PARENT DRUG): MUSCLE, LIVER AND FAT (CATTLE, SHEEP, PIGS, GOATS, TURKEYS, DUCKS AND CHICKENS), EGGS (CHICKENS), MILK (CATTLE): 0.5; KIDNEY (CATTLE, SHEEP, PIGS, GOATS, TURKEYS, DUCKS AND CHICKENS): 5. TE. TMRL 1968, NMRS 45/TRS 430-JECFA 12/16, FAS 69.34/NMRS 45A-JECFA 12/6, NMRS 45/TRS 430-JECFA 12/16. ACCEPTABLE LEVELS OF RESIDUES (CALCULATED AS BASE): MILK: 0-0.15; MEAT: 0-0.5; EGGS: 0-0.2. NO. N |
| 3 Mar 04 | |
See Also:
Toxicological Abbreviations
Neomycin (JECFA Food Additives Series 51)
Neomycin (WHO Food Additives Series 34)
Neomycin (WHO Food Additives Series 38)