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Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

CEFTIOFUR
Chemical names: [6R-[6alpha,7BETA(Z)]]-7-[[(2-AMINO-4-THIAZOLYL)(METHOXYIMINO)ACETYL]AMINO]-3-[[2-FURANYLCARBONYL)THIO]METHYL]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2- CARBOXYLIC ACID; CEFTIOFUR MONOHYDROCHLORIDE; (6R-7R)-7-[[2-AMINO-4-THIAZOLYL)-Z-(METHOXYIMINO)ACETYL]AMINO]-3-[[(2-FURANYLCARBONYL)THIO]METHYL]-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-CARBOXYLIC ACID, MONOHYDROCHLORIDE
Synonyms: CEFTIOFUR SODIUM; Na CEFTIOFUR; CEFTIOFUR MONOHYDROCHLORIDE; TRADE NAMES: NAXCEL, EXCENEL
Functional class: VETERINARY DRUG (ANTIMICROBIAL AGENT)
Latest evaluation: 1997
ADI: 0-0.05 mg/kg bw (1995)
Comments/MRLs: MRLs (expressed as desfuroylceftiofur, in mg/kg tissue, mg/l milk): Muscle (cattle and pigs): 1; Liver and fat (cattle and pigs): 2; Kidney (cattle and pigs): 6; Milk (cattle): 0.1
Report: TRS 879-JECFA 48/11
Residues: FNP 41/10-JECFA 48/1
Tox monograph: FAS 36-JECFA 45/61
Previous status: 1995, TRS 864-JECFA 45/26, FNP 41/8-JECFA 45/9, FAS 36-JECFA 45/61. 0.05. MRLs (EXPRESSED AS DESFUROYLCEFTIOFUR): MUSCLE (CATTLE AND PIGS): 0.2; LIVER (CATTLE AND PIGS): 2; KIDNEY (CATTLE AND PIGS): 4; FAT (CATTLE AND PIGS): 0.6; MILK (CATTLE): 0.1. FU. MRL
 
12 Nov 01    




    See Also:
       Toxicological Abbreviations
       Ceftiofur (WHO Food Additives Series 36)