| DIHYDROSTREPTOMYCIN | |
| Chemical names: | O-2-DEOXY-(METHYLAMINO)-alpha-L-GLUCOPYRANOSYL-(1?>2)-O-5-DEOXY-3C- (HYDROXYMETHYL)-alpha-L-LYXOFURANOSYL-(1?>4)-N,N'-bis(AMINOIMINOMETHYL)-D- STREPTAMINE | Functional class: | VETERINARY DRUG (ANTIMICROBIAL AGENT) | Latest evaluation: | 2002 | ADI: | 0-0.05 mg/kg bw (1997) | Comments: | Group ADI for dihydrostreptomycin and streptomycin, established at the forty-eighth meeting (1997). | Comments/MRLs: | MRLs (expressed as the sum of the concentrations of dihydrostreptomycin and streptomycin): Milk (cattle and sheep): 0.2 mg/kg. The MRLs recommended at the fifty-second meeting (1999) were not reconsidered and were maintained. | Report: | TRS 911-JECFA 58/26 | Residues: | FNP 41/14-JECFA 58/37 | Tox monograph: | FAS 39-JECFA 48/39 (1997) | Previous status: | 1999, TRS 893-JECFA 52/20, FNP 41/12-JECFA 52/21, FAS 39-JECFA 48/39 (1997). 0-0.05 mg/kg bw (1997). MRLs (EXPRESSED AS THE SUM OF THE CONCENTRATIONS OF DIHYDROSTREPTOMYCIN AND STREPTOMYCIN): MUSCLE, LIVER AND FAT (CATTLE, SHEEP, PIGS AND CHICKENS): 0.6 mg/kg; KIDNEY (CATTLE, SHEEP, PIGS AND CHICKENS): 1 mg/kg; MILK (CATTLE): 0.2 mg/l (TEMPORARY). FU. MRL/TMRL (MILK)
1997, TRS 879-JECFA 48/25, FNP 41/10-JECFA 48/39, FAS 39-JECFA 48/39. 0-0.05. GROUP ADI FOR DIHYDROSTREPTOMYCIN AND STREPTOMYCIN. MRLs (TEMPORARY, ESTABLISHED AT THE 43rd MEETING; EXPRESSED AS THE SUM OF THE CONCENTRATIONS OF DIHYDROSTREPTOMYCIN AND STREPTOMYCIN): MUSCLE, LIVER AND FAT (CATTLE, SHEEP, PIGS AND CHICKENS): 0.5; KIDNEY (CATTLE, SHEEP, PIGS AND CHICKENS): 1; MILK (CATTLE): 0.2. FU. TMRL 1994, TRS 855-JECFA 43/9, FNP 41/7-JECFA 43/17, FAS 34-JECFA 43/11, 0-0.03 (TEMPORARY), MRLs (TEMPORARY; EXPRESSED AS THE SUM OF THE CONCENTRATIONS OF DIHYDROSTREPTOMYCIN AND STREPTOMYCIN): MUSCLE, LIVER AND FAT (CATTLE, SHEEP, PIGS AND CHICKENS): 0.5; KIDNEY (CATTLE, SHEEP, PIGS AND CHICKENS): 1; MILK (CATTLE): 0.2 (GROUP TEMPORARY ADI FOR DIHYDROSTREPTOMYCIN AND STREPTOMYCIN, INDIVIDUALLY OR IN COMBINATION), TE, TMRL 1968, NMRS 45/TRS 430-JECFA 12/16, FAS 69.34/NMRS 45A-JECFA 12/4, NMRS 45/TRS 430-JECFA 12/16. ACCEPTABLE LEVELS OF RESIDUES (CALCULATED AS BASE): MILK: 0-0.2; MEAT: 0-1.0; EGGS: 0-0.5. NO. N |
| 1 Feb 03 | |
See Also:
Toxicological Abbreviations
Dihydrostreptomycin (WHO Food Additives Series 34)