International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 7 (1974) (p. 203)

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Benzene has been tested only in mice by subcutaneous injection and skin application. The data reported do not permit the conclusion that carcinogenic activity has been demonstrated.

5.2 Human carcinogenicity data

It is established that exposure to commercial benzene or benzene-containing mixtures may result in damage to the haematopoietic system. A relationship between such exposure and the development of leukaemia is suggested by many case reports, and this suggestion is strengthened by a case-control study from Japan.

Subsequent evaluation: Vol. 29 (1982); Suppl. 7 (1987)

Last updated: 19 March 1998

    See Also:
       Toxicological Abbreviations
       Benzene (EHC 150, 1993)
       Benzene (ICSC)
       BENZENE (JECFA Evaluation)
       Benzene (PIM 063)
       Benzene (IARC Monograph, Volume 120, 2018)
       Benzene  (IARC Summary & Evaluation, Supplement7, 1987)
       Benzene (IARC Summary & Evaluation, Volume 29, 1982)