International Agency for Research on Cancer (IARC) - Summaries & Evaluations


VOL.: 12 (1976) (p. 245)

CAS No.: 12122-67-7
Chem. Abstr. Name: {[l,2-Ethanediylbis(carbamodithioato)] (2-)}zinc

5. Summary of Data Reported and Evaluation

5.1 Animal carcinogenicity data

Zineb produced an increased incidence of lung tumours after its oral administration to mice of one strain. Systemic reticular-cell sarcomas were observed in mice and a variety of sarcomas in rats after its subcutaneous administration. No increases in tumour incidences were observed in two other strains of mice and in two limited studies in rats following oral administration. The available data do not allow an evaluation of the carcinogenicity of zineb to be made.

5.2 Human carcinogenicity data

No case reports or epidemiological studies were available to the Working Group.

Subsequent evaluation: Suppl. 7 (1987) (p. 74: Group 3)

For definition of Groups, see Preamble Evaluation.


Last updated: 25 March 1998

    See Also:
       Toxicological Abbreviations
       Zineb (ICSC)
       Zineb (FAO Meeting Report PL/1965/10/1)
       Zineb (FAO/PL:1967/M/11/1)
       Zineb (Pesticide residues in food: 1993 evaluations Part II Toxicology)