PESTICIDE RESIDUES IN FOOD - 1979 Sponsored jointly by FAO and WHO EVALUATIONS 1979 Joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues Geneva, 3-12 December 1979 METHAMIDOPHOS Explanation This compound was evaluated in 1976. The 1979 CCPR decided to ask the Meeting to re-evaluate the data because several delegations felt that the recommended MRLS were higher than necessary. Comments on the significance of methamidophos as a residue from acephate application were also solicited. This specifically relates to whether the MRLs for methamidophos would be exceeded from applications of acephate considering that in several crops, acephate has higher MRLs than methamidophos. RESIDUES IN FOOD AND THEIR EVALUATION The 1976 data on cauliflower, cucumber, eggplants and sugar beets are summarized in Table 1. It is seen that there are enough grounds for lowering the MRLS for these commodities. In the case of alfalfa, soybeans and citrus fruit, the MRLs are necessary to take account of methamidophos residues as a result of acephate application since MRLS for acephate have been allocated for these crops. The data in 1976 for acephate can be used as the basis in this MRL. Table 1. Residues from acephate and methamidophos application (from FAO/WHO 1977) Acephate (mg/kg) Methamidophos Based on Based on Commodity Residues1 MRL PHI Residues2 MRL PHI (days) (days) Cauliflower 2.3-4.4 5 14 0.5 2 14 Cucumbers - 0.03-0.3 1 7 Eggplants - 0.05-0.06 1 7 Sugarbeets n.d.-0.05 1 21 0.01(23) 21 n.d. (28) 1 Combined acephate and methamidophos residues; 2 No PHI recorded in 1976 but the values shown could be the basis for the recommended MRLs. From Table 1 the meeting was able to estimate the maximum residue levels which are likely to occur when methamidophos was used in practice and when the reported intervals between last application and harvest were observed. Further, the 1976 data for acephate is sufficient to estimate maximum residue levels for methamidophos which could result from acephate application to alfalfa, citrus fruit and soybeans. Additional data would be required if methamidophos are applied on these crops. RECOMMENDATIONS The following new Maximum Residue Limits are recommended: Commodity MRL Preharvest intervals on which based Alfalfa 2 Cauliflower 1 14 Citrus 0.5 Cucumber 0.5 3 Eggplant 0.1 14 Soybeans 0.05 Sugarbeets 0.03 FURTHER WORK OR EVALUATION Desirable 1. Residue data on alfalfa, citrus and soybeans arising from the application of methamidophos; 2. Information on use patterns from countries where methamidophos is used; 3. Further information on the level and fate of residues during cooking and processing of fruit and vegetables.
See Also: Toxicological Abbreviations Methamidophos (HSG 79, 1993) Methamidophos (ICSC) Methamidophos (JMPR Evaluations 2002 Part II Toxicological) Methamidophos (Pesticide residues in food: 1976 evaluations) Methamidophos (Pesticide residues in food: 1981 evaluations) Methamidophos (Pesticide residues in food: 1982 evaluations) Methamidophos (Pesticide residues in food: 1984 evaluations) Methamidophos (Pesticide residues in food: 1985 evaluations Part II Toxicology) Methamidophos (Pesticide residues in food: 1990 evaluations Toxicology)