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    PESTICIDE RESIDUES IN FOOD - 1983


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    EVALUATIONS 1983





    Data and recommendations of the joint meeting
    of the FAO Panel of Experts on Pesticide Residues
    in Food and the Environment and the
    WHO Expert Group on Pesticide Residues
    Geneva, 5 - 14 December 1983

    Food and Agriculture Organization of the United Nations
    Rome 1985

    DIFLUBENZURON

    RESIDUES

    Explanation

           Diflubenzuron was first evaluated in 1981.1  The attention of
    the Meeting was drawn to the fact that the data supporting the 1981
    estimates for maximum residue levels (MRLs) in Brussels sprouts,
    cabbage and plums had been inadvertently omitted from the 1981
    evaluations. This addendum corrects that error.

    RESIDUES IN FOOD AND THEIR EVALUATION

    RESIDUES RESULTING FROM SUPERVISED TRIALS

           Two supervised trials on Brussels sprouts in 1976 in the
    Netherlands resulted in residues of up to approximately 0.3 mg/kg in
    harvested crops 58 days after treatment (see Table 1, Philips-Duphar
    1978a). Trials on cabbage in the Netherlands in 1974 and the Federal
    Republic of Germany in 1975 showed that initial residues in Savoy
    cabbage of up to 0.7 mg/kg declined to 0.1 mg/kg or less in 28 days.
    Similarly, in oxheart cabbage, initial residues of up to 3 mg/kg
    declined to about 0.1 mg/kg or less in 28 days (see Table 1, 
    Philips-Duphar 1976).

           In Brussels sprouts, the analytical method gave a mean recovery
    of 88 percent over a range of diflubenzuron from 0.02 mg/kg to 2
    mg/kg. Mean recoveries for Savoy cabbage were 92 percent and for
    oxheart cabbage 85 percent, both over a range of 0.03 mg/kg to 2
    mg/kg. The limit of determination was from 0.02 mg/kg for Brussels
    sprouts to 0.05 mg/kg for cabbage.

           A single trial on Victoria plums in 1977 in the Netherlands
    showed a residue of less than 0.1 mg/kg 27 days after treatment. Mean
    recoveries with the analytical method were 98 percent over a range of
    0.01 mg/kg (the limit of determination) to 2 mg/kg of diflubenzuron
    (see Table 1, Philips-Duphar 1977).

              

    1 See Annex 2 for FAO and WHO documentation.

        Table 1   Diflubenzuron residues in Brussels sprouts, cabbage and plums

                                                                                                 

                                           Interval from application           Residue
    Crop                 Treatment         to sampling (days)                  (mg/kg)
                                                                                                 

    Brussels sprouts     0.001%                     15                           0.07
    (Netherlands)        conc'n spray               58                          <0.02
    1976                 0.01%                      16                           0.33
                         conc'n spray               58                           0.31

    Brussels sprouts     250 g a.i./ha               7                           0.94
    (UK)                                            14                           0.81
    19781                                            21                           0.6
                                                    28                           0.68

    Savoy cabbage        25 g a.i. in                0                  0.7, 0.24, 0.39, 0.23
    (Netherlands)        2 500 l water/
    1974                 ha                          7                  0.13, 0.22, 0.22, 0.08,
                                                    14                  0.21, 0.17, 0.10, 0.05
                                                    28                  0.03,<0.03, <0.03, <0.03
                                                     0                  0.22, 0.45, 0.14,<0.03
                                                     7                  0.08, 0.20, 0.10, 0.07
                                                    14                  0.06, 0.09, 0.10, 0.03
                                                    28                  0.06, 0.11, 0.08, 0.06

    Oxheart              100 g a.i. in               0                  1.8, 2.9, 2.0, 2.9
    Cabbage              1 000 l                     7                  0.9, 0.6, 1.2, 0.9
    (Germany)            water/ha                   14                  0.4, 0.3, 0.5, 0.4
    1975                                            28                  0.07, 0.06, 0.1, 0.1

    Plums                0.02%                      27                  0.02
    (Netherlands )       conc'n
    1976                 0.04%                      27                  0.06
                         conc'n
                                                                                                 

    1    Source: Philips-Duphar 1978b.
    
    APPRAISAL

           The Meeting reviewed the data on residues in mushrooms in the
    1981 evaluations and concluded that an estimated MRL of 0.1 mg/kg was
    more appropriate than the figure of 0.2 mg/kg previously estimated. It
    was recognized, however, that at the highest rate of application
    studied there was a possibility the 0.1 mg/kg might be marginally
    exceeded at the first cropping. The Meeting noted that the data
    supporting the 1981 estimates for MRLs in Brussels sprouts, cabbage
    and plums had been accidentally omitted from the 1981 evaluations. On
    reviewing these data, the Meeting concluded that they would not
    support the MRL for plums estimated in 1981 and recommended that it be
    withdrawn until further data become available.

    REFERENCES- RESIDUES

    Philips-Duphar Report on residues of diflubenzuron in cabbage,
    1976          Netherlands 1974, Germany 1975. (Unpublished)

    Philips-Duphar Report on residues of diflubenzuron in plums,
    1977          Netherlands 1976. (Unpublished)

    Philips-Duphar Report on residues of diflubenzuron in Brussels
    1978a         sprouts, Netherlands 1976. (Unpublished)

    Philips-Duphar Report on residues of diflubenzuron in Brussels
    1978b         sprouts, UK 1978. (Unpublished)


    See Also:
       Toxicological Abbreviations
       Diflubenzuron (EHC 184, 1996)
       Diflubenzuron (HSG 99, 1995)
       Diflubenzuron (Pesticide residues in food: 1981 evaluations)
       Diflubenzuron (Pesticide residues in food: 1984 evaluations)
       Diflubenzuron (Pesticide residues in food: 1985 evaluations Part II Toxicology)
       Diflubenzuron (JMPR Evaluations 2001 Part II Toxicological)