PESTICIDE RESIDUES IN FOOD - 1980
Sponsored jointly by FAO and WHO
EVALUATIONS 1980
Joint meeting of the
FAO Panel of Experts on Pesticide Residues
in Food and the Environment
and the
WHO Expert Group on Pesticide Residues
Rome, 6-15 October 1980
COUMAPHOS
TOXICOLOGY
This insecticide was first evaluated in 1968 when a temporary ADI
was recommended. Short-term studies of the main metabolites,
including histopathology and biochemical studies, cholinesterase
inhibition studies and haematological studies, including
coagulation effects in man, were required by 1972. These studies
were requested in 1972, 1975, 1978 and 1980 but were not made
available.
The Meeting therefore decided to withdraw the temporary ADI.
Residues and analytical aspects
As the temporary ADI for coumaphos was withdrawn, the temporary
MRLs were converted to Guideline Levels. These are recorded in
Annex. 1.