FAO/PL:1969/M/17/1 WHO/FOOD ADD./70.38 1969 EVALUATIONS OF SOME PESTICIDE RESIDUES IN FOOD THE MONOGRAPHS Issued jointly by FAO and WHO The content of this document is the result of the deliberations of the Joint Meeting of the FAO Working Party of Experts and the WHO Expert Group on Pesticide Residues, which met in Rome, 8 - 15 December 1969. FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS WORLD HEALTH ORGANIZATION Rome, 1970 PYRETHRINS AND PIPERONYL BUTOXIDE Explanation These pesticides were evaluated by the 1966, 1967 and 1968 Joint Meetings (FAO/WHO, 1967b, 1968b, 1969b).* At the Fourth Session (1969) of the Codex Committee on Pesticide Residues the delegation of Canada pointed out the need for tolerances for residues of pyrethrins and piperonyl butoxide on dried codfish. Supporting data were submitted and evaluated at this 1969 Joint Meeting. RESIDUES IN FOOD AND THEIR EVALUATION CODFISH The use of pyrethrins piperonyl botoxide emulsions to protect light salted codfish from blow fly attack during the drying process is practised in Newfoundland and possibly elsewhere. The technology for protection against the species Lucillia illustris (Meig) and Calliphora terranovae (Macq.) has been described (Morris and Andrews, 1968). Fish taken from brine barrels are washed in salt water and dipped in insecticide emulsion for 3-5 seconds. They are immediately spread on trays to dry in the sun and wind. Recently it has been found possible to reduce the concentration of insecticide in the emulsion to 0.0625 percent pyrethrins and 0.125 percent piperonyl butoxide (technical) and still maintain protection. Residues resulting from supervised trials on codfish Fifty fish were dipped in the emulsion (0.0625 percent pyrethrins, 0.125 percent piperonyl butoxide) and fifty fish were left untreated as checks on 14 September 1968. Following drying in regular commercial manner, treated and untreated fish were sampled on 23 October and shipped by air for analysis. The analyses were carried out by a method reported by McGlaughlin Gormley King Co. based on the use of a gas chromatographic method and detector cell described by Bruce (Bruce, 1967). Replicated analyses showed levels of 0.051 to 0.066 ppm pyrethrins and 0.76 to 0.97 ppm piperonyl butoxide (0.87 to 1.1 ppm technical) in the fish. This is representative of residues in the product as moving in commerce. Such fish would be soaked or boiled in water before consumption. Methods of residue analysis The methods of analysis outlined above should be evaluated for use as regulatory methods. They have been reported to the IUPAC Commission on Development, Improvement and Standardization of Methods of Pesticide Residue Analysis. FRESH FRUIT AND VEGETABLES The new data that had been mentioned at the Fourth Session of the Codex Committee on Pesticide Residues were not available for consideration at the meeting. Whilst examining the data available it was noted that the monograph for the 1968 meeting (FAO/WHO, 1969b) contained the reservation "for canning only" against the recommendation for a tolerance for piperonyl butoxide but not for pyrethrins. Recommendation After discussion it was decided that the limiting words should be deleted from the recommendations pertaining to piperonyl butoxide. RECOMMENDATIONS FOR TEMPORARY TOLERANCES The following temporary tolerances, to be in effect until 1972: a) Dried codfish moving in commerce: pyrethrins - 0.1 ppm piperonyl butoxide - 1.0 ppm b) Fresh fruit and vegetables (amendment) The words "for canning only" should be deleted from the recommendations included in the records of previous meetings, FURTHER WORK REQUIRED (by 30 June 1972) In addition to "Further Work" included in FAO/WHO 1967b) and 1968b, experience and residue data from similar trials with dried fish in other countries. REFERENCES Bruce, W.N. (1967) Detection cell for measuring picogram quantities of organophosphorus insecticides, pyrethrins synergists and other compounds by gas chromatography. J.Agr.Fd.Chem. 15: 178-81 Morris, R.F. and Andrews, D. (1968) Investigations into the use of pyrethrins and other insecticides for the control of blowfly. Calliphura terranovae (Macq.) infesting light salted codfish in Newfoundland. Purethrum Post 9: 9-13 * See Appendix II
See Also: Toxicological Abbreviations Piperonyl butoxide (ICSC) Piperonyl Butoxide (FAO Meeting Report PL/1965/10/1) Piperonyl butoxide (FAO/PL:CP/15) Piperonyl butoxide (FAO/PL:1967/M/11/1) Piperonyl butoxide (WHO Pesticide Residues Series 2) Piperonyl butoxide (Pesticide residues in food: 1992 evaluations Part II Toxicology) Piperonyl butoxide (Pesticide residues in food: 1995 evaluations Part II Toxicological & Environmental) Piperonyl Butoxide (IARC Summary & Evaluation, Volume 30, 1983)