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    PESTICIDE RESIDUES IN FOOD - 1984


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    EVALUATIONS 1984




    The monographs



    Data and recommendations of the joint meeting
    of the FAO Panel of Experts on Pesticide Residues
    in Food and the Environment and the
    WHO Expert Group on Pesticide Residues
    Rome, 24 September - 3 October 1984

    Food and Agriculture Organization of the United Nations
    Rome 1985

    CHLORDANE

    Explanation

         Chlordane was evaluated by the Joint Meeting in 1965, 1967, 1969,
    1970, 1972, 1974, 1977 and 1982. 1/  Governments were requested to
    provide information on uses, maximum residue limits and data from
    monitoring of chlordane residues in food to enable the meeting to re-
    evaluate the compound. At the 14th Session of the CCPR, a proposal was
    made to change MRLs to ERLs, and doubt was expressed whether the
    proposed residue limits correspond to the existing situation in regard
    to use pattern and the presence of residues in food from environmental
    contamination.

    RESIDUES IN FOOD AND THEIR EVALUATION

    USE PATTERN

         The meeting received information on current approved uses of
    chlordane in Canada (1984) and Mexico (1984) [Table 1]. Information
    was also received that all agricultural uses have been discontinued in
    the Netherlands (1984) since 1974 and in the United States (1984)
    since 1980, and that the compound has been banned in food crops in all
    countries in the European Economic Communities since 1981. The only
    registered use in the United Kingdom (1984) is in ornamental and
    amenity turf.

    RESIDUES IN FOOD IN COMMERCE OR AT CONSUMPTION

         Monitoring data were provided by the United States from the Food
    and Drug Administration (FDA) Domestic Surveillance Program (Table 2).

         Monitoring data were also provided from the United States (1984)
    by the U.S. Department of Agriculture monitoring of animal products
    (Tables 3 and 4).



              

    1/  See Annex 2 for FAO and WHO documentation.


        TABLE 1.  Registered and Approved Uses for Chlordane

                                                                                                           

    Country        Commodity             Approved           Applications           Limitations
                                         Application
                                         Rate
                                         (kg a.i./ha)
                                                                                                           

    Canada 2       Strawberry            5.5-11             Soil treatment,        No root crops in
                                                            broadcast before       treated soil for
                                                            planting               4 years after
                                                                                   treatment

                                         1.1-2.25           Soil treatment,
                                                            band, at planting

                   Bean, beet,           5.5-11             Soil treatment,        Only applied once
                   broccoli,                                broadcast, before      for every 4 years
                   Brussels sprouts,                        planting               or more. Treated
                   cabbage,                                                        crop should not be
                   cauliflower,                                                    used as feed for
                   cucumber, kale,                                                 livestock
                   lettuce, melons,
                   onion, potato,        1.1-2.25           Soil treatment,
                   radish & tomato                          band, at planting

    Mexico         Sorghum & maize       1.5-2.0            Soil treatment,
                                                            band, at sowing
                                                                                                           

    1  See Annex 2 for FAO and WHO documentation.
    2  Chlordane is also used in ornamentals and turf.

    TABLE 2.  Chlordane Residues, United States 1

                                                                                                            

    Commodity Group               No. of samples      No. with residues        Range of
    (Codex Class. No.                                 of chlordane (cis,       residues
                                                      trans, oxychlordane
                                                      and nonachlor)           (mg/kg)
                                                                                                            

    Grains                            1 207                  2                 0.03-0.09
    (A03.15)

    Milk and milk                     2 534                 56                 <0.01-0.07
    products
    (BO7.28-29)

    Eggs                              1 773                 34                 <0.01-2.1 2
    (BO8.33)

    Fruit and fruit products          4 777                  3                 0.01-0.13
    (AO2.9-14)

    Vegetables and                    11 779               119                 <0.01-0.60
    vegetable products
    (a01.1-8)
                                                                                                            

    1  Data gathered from 1 October 1979 to 30 September 1983.
    2  Data included from an incident of chlordane misuse in and around poultry houses. 
       1981-83 surveillance programme showed seven positive out of 1 219 samples 
       (range <0.01-0.02 mg/kg).

    TABLE 3.  Chlordane Residues in the Carcase of Horses, Bulls/Cows, Heifers/Steers, Calves, Sheep, 
              Goats, Pigs and Rabbits

                                                                                                     

                                  1979          1980          1981          1982         1983
                                                                                                     

    No. of samples               3 638         4 537         2 763         2 656        4 725

    No. of residues                 31            46            70            54          137
    > 0.02 mg/kg of
    chlordane (cis, trans,
    oxychlordane and
    nonachlor)

    No. of residues                 15            24            30            28           37
    exceeding Codex ERL:
    0.05 mg/kg

    Range of residues        0.02-0.24     0.02-0.77     0.02-0.23     0.02-0.60    0.02-1.04
    (mg/kg)                     (3.16)                      (6.24)        (6.57)  (2.43-2.95)
                                                                                                     

    TABLE 4.  Chlordane Residues in the Carcase Fat of Poultry (Chickens, Turkeys, Ducks, Geese)

                                                                                                     

                                  1979          1980          1981          1982         1983
                                                                                                     

    No. of samples               1 066         1 984         1 674         1 386        1 744

    No. of samples with              2             2             5             7           12
     residues > 0.02 mg/kg
     chlordane (cis, trans,
     oxychlordane, nonachlor)

    No. of residues                  0             2             3             2            5
    exceeding Codex ERL:
    0.05 mg/kg

    Range of residues        0.02-0.03     0.02-0.46     0.02-0.10     0.02-0.11    0.02-0.13
                                                                          (0.85)       (0.50)
                                                                                                     
    


    NATIONAL MAXIMUM RESIDUE LIMITS REPORTED TO THE MEETING

         Updated lists of MRLs were provided to the Meeting by Canada
    (1984) and The Netherlands (1984).

                                                                

    Country        Commodity                         MRL (mg/kg)
                                                                

    Canada         Butter, cheese, milk              0.1
                   and other dairy products
                   (on fat basis)

                   Meat, meat by-products of         0.1
                   cattle, goat, hog, sheep and
                   poultry (on fat basis)

    Holland        Pineapple                         0.1
                   Other fruit                       0.02
                   Cucumber and melon                0.1
                   Other vegetables                  0.02
                   Pulses                            0.02
                   Cereals                           0.05
                   Potato                            0.05
                   Vegetable oil                     0.02
                   All other plant products          0 (0.02)
                   Milk                              0.002
                   All other animal products         0.05
                    (on fat basis)
                                                                

         The United States (1984) informed the meeting that although
    chlordane is no longer registered for uses on food crops, maximum
    residue limits from approved uses in the past remain in effect. This
    country intends to substitute existing residue limits with action
    levels (the equivalent of Codex ERLs) for food containing residues
    from environmental contamination.

    APPRAISAL

         Governments were requested to provide the JMPR with information
    on uses, national MRLs and monitoring data for chlordane in food in
    order to enable the meeting to re-evaluate the compound. Doubt has
    been expressed whether proposed Codex residue limits correspond to
    current use patterns and to the presence of residues in food from
    environmental contamination.

         The meeting was informed that agricultural uses of chlordane have
    been discontinued in a number of countries but remain for food crops
    in Canada (vegetables, including potato and strawberry) and Mexico
    (sorghum and maize).

         Extensive monitoring data were provided by the United States from
    the FDA Surveillance Program 1979-83. This programme includes analysis
    of cereals, vegetables, milk, milk products and eggs. About 0.1-0.2
    percent of the grain and fruit samples and about 1 percent of the
    vegetable samples analysed contained chlordane residues. Chlordane was
    detected in about 2 percent of the samples of milk, milk products and
    eggs. The limit of detection in this programme was 0.01 mg/kg.

         Data were also received from the U.S. Department of Agriculture
    monitoring programme on the analysis for chlordane in fat from animals
    and poultry. Chlordane residues were detected in 1-3 percent (average
    1.8 percent) of the samples of carcase fat from animals with a limit
    of detection of 0.02 mg/kg. In 0.5-1 percent (average 0.7 percent) of
    the samples the residues exceeded the Codex ERL of 0.05 mg/kg.

         Chlordane residues were detected in 0.1-0.7 percent (average
    0.36 percent) of the samples analysed of carcase fat from poultry. In
    0-0.3 percent (average 0.15 percent), residues exceeded the Codex ERL
    of 0.05 mg/kg.

         During 1979-83, no decrease in the frequency of detection or the
    levels of chlordane residues was observed. The frequency of detection
    appeared to increase during the period, but as most figures are at or
    about the limit of determination this increase is hardly significant.

    RECOMMENDATIONS

         Chlordane is still in use in some countries for the treatment of
    vegetables and cereals, and monitoring data have proved that residues
    are present, although in a limited number of samples, especially of
    vegetables and animal products. The meeting recommends maintaining the
    existing residue limits in vegetables and animal products.

         Chlordane is rarely found in cereals and fruit, and residues are
    very low. The meeting recommends, for this reason, that residue limits
    for chlordane in fruit and cereals grains (except sorghum and maize)
    be lowered from 0.05 mg/kg to 0.02 mg/kg.

                                             

         Commodity           ERL (mg/kg)
                                             

         Almonds             0.02
         Bananas             0.02
         Figs                0.02
         Guavas              0.02
         Mangoes             0.02
         Papayas             0.02
         Passion fruit       0.02
         Pecans              0.02
         Pineapples          0.02
         Pomegranates        0.02
         Rice (polished)     0.02
         Rye                 0.02
         Strawberries        0.02
         Walnuts             0.02
         Wheat               0.02
                                             


    REFERENCES

    Canada. Information on chlordane submitted by Canada to FAO.
    1984

    Mexico. Information on chlordane submitted by Mexico to FAO.
    1984

    Netherlands. Information on chlordane submitted by the Netherlands to
    1984      FAO.

    United Kingdom. Information on chlordane submitted by the United
    1984      Kingdom to FAO.

    United States. Information on chlordane submitted by the U.S. Food and
    1984      Drug Administration and the U.S. Department of Agriculture
              to FAO.


    See Also:
       Toxicological Abbreviations
       Chlordane (EHC 34, 1984)
       Chlordane (HSG 13, 1988)
       Chlordane (PIM 574)
       Chlordane (FAO Meeting Report PL/1965/10/1)
       Chlordane (FAO/PL:1967/M/11/1)
       Chlordane (FAO/PL:1969/M/17/1)
       Chlordane (AGP:1970/M/12/1)
       Chlordane (WHO Pesticide Residues Series 2)
       Chlordane (WHO Pesticide Residues Series 4)
       Chlordane (Pesticide residues in food: 1977 evaluations)
       Chlordane (Pesticide residues in food: 1982 evaluations)
       Chlordane (Pesticide residues in food: 1986 evaluations Part II Toxicology)