JECFA Evaluations-DELTAMETHRIN-

Summary of Evaluations Performed by the
Joint FAO/WHO Expert Committee on Food Additives

DELTAMETHRIN
Chemical names:	S-CYANO-3-PHENOXYBENZYL-cis-(1R,3R)-3-(2,2-DIBROMOVINYL)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLATE
Synonyms:	RU 22974; DECAMETHRIN: BUTOX®
Functional class:	VETERINARY DRUG (INSECTICIDE)
Latest evaluation:	2003
ADI:	0-0.01 mg/kg bw (2000)
Comments/MRLs:	An intake assessment was performed at the sixtieth meeting (2003), which affirmed that the MRLs listed below that were recommended at the fifty-second meeting were compatible with the ADI OF 0-0.01 mg/kg bw established by the 2000 Joint FAO/WHO Meeting on Pesticide Residues (JMPR; FAO Plant Production and Protection Paper 163, Rome, 2001). MRLs (expressed as the parent drug, in mg/kg): Muscle (cattle, sheep, chickens, salmon): 0.03; Liver and kidney (cattle, sheep, chickens): 0.05; Fat (cattle, sheep, chickens): 0.5; Milk (cattle): 0.03; Eggs (chicken): 0.03. The concentrations of residues in muscle, milk and eggs were very low; these MRLs are for guidance only and are based on two times the limit of quantitation of the analytical method.
Report:	TRS 918-JECFA 60/19
Residues:	FNP 41/15-JECFA 60/21
Tox monograph:	See Pesticide Residues in Food - 2000 evaluations, Part II - Toxicological. World Health Organization, WHO/PCS/01.3, Geneva, 2001
Previous status:	1999, TRS 893-JECFA 52/37, FNP 41/12-JECFA 52/1. 0-0.01 mg/kg bw (1982 JMPR, FAO PLANT PRODUCTION AND PROTECTION PAPER 46, ROME, 1983). MRLs (EXPRESSED AS THE PARENT DRUG, IN MG/KG): MUSCLE (CATTLE, SHEEP, CHICKENS, SALMON): 0.03; LIVER AND KIDNEY (CATTLE, SHEEP, CHICKENS): 0.05; FAT (CATTLE, SHEEP, CHICKENS): 0.5; MILK (CATTLE): 0.03; EGGS (CHICKENS): 0.03. THE CONCENTRATIONS OF RESIDUES IN MUSCLE, MILK AND EGGS WERE VERY LOW; THESE MRLs ARE FOR GUIDANCE ONLY AND ARE BASED ON TWO TIMES THE LIMIT OF QUANTITATION OF THE ANALYTICAL METHOD. FU. MRL.

8 Jan 05