FAO PLANT PRODUCTION AND PROTECTION PAPER 15 Sup. Pesticide Residues In Food: 1978 Evaluations The Monographs Data And Recommendations Of The Joint Meeting Of The FAO Panel Of Experts On Pesticide Residues And The Environment And The WHO Expert Group On Pesticide Residues, Rome 27 Novembre-6 December 1978 FOOD AND AGRICULTURE ORGANIZATION OF THE UNITED NATIONS Rome 1979 The designation employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations concerning the legal status of any country, territory, city of area or of its authorities, or concerning the delimitation of its frontiers or boundaries. M-84 ISBN 92-5-100828-0 The copyright in this book is vested in the Food and Agriculture Organization of the United Nations. The book may not be reproduced, in whole or in part, by any method or process, without written permission from the copyright holder. Applications for such permission, with the statement of the purpose and extent of the reproduction desired, should be addressed to the Director, Publications Division, Food and Agriculture Organization of the United Nations, Via delle Terme di Caracalla, 00100 Rome, Italy. (C) FAO 1979 This document contains summaries of the data considered by the Joint Meeting of the FAO Panel of Experts on Pesticide Residues and the Environment and the WHO Expert Group on Pesticide Residues, which met in Rome, 27 November - 6 December, 1978, together with the recommendations made. A Report of the 1978 Joint Meeting, which outlines the principles on which the evaluations were carried out and summaries the recommendations made, has also been published.* * Pesticide Residues in Food: Report of the 1978 Joint Meeting of the FAO Panel of Experts on Pesticide Residues and the Environment and the WHO Export Group on Pesticide Residues, FAO Plant Production and Protection Series No. 15, 1979. CONTENTS List of attendees Introduction The Monographs (When the consideration or issues concerning a compound is fully covered by a statement appearing in the Report of the Meeting, the present volume only provides a reference to the relevant section of the Report). Acephate* (See Report section 3.7) Aminocarb Benomyl* (See Report section 3.3) Bromophos* (See Report section 3.7) Bromophos-ethyl* (See Report section 3.7) Bromopropylate* (See Report section 3.7) sec-BUTYLAMINE* Captan* Carbendazim* Cartap* Chlordane* (See Report section 3.2) Chlordimeform* Chlormequat* (See Report section 3.7) Chlorothalanil* Coumaphos* Cyanofenphos* (See Report section 4.16) Cyhexatin* DDT* (See Report section 3.5) Dialifos* (See Report section 3.7) Dimethoate* (See Report section 3.4) Diphenylamine* (See Report section 4.21) Diquat* Disulfoton* Endosulfan* (See Report section 3.7) Ethephon Ethiofencarb* Fenamiphos* Fenthion* Formothion* (See Report section 3.4) Guazatine HCH* (See Report section 3.6) Heptachlor* (See Report section 3.2) Hexachlorobenzene* (See Report section 4.33) Leptophos* Lindane* Methomyl* Omethoate* Paraquat* Parathion-methyl* Phosmet* Pirimicarb* Propargite* Propoxur* (See Report section 3.7) Quintozene* (See Report section 4.44) Tecnazene* Thiofanox (See Report section 4.46) Thiophanate-methyl* (See Report section 3.3) Trichlorfon* Triforine* Vinclozolin (See Report section 3.50) ANNEX 1 - Table of Acceptable Daily Intakes, Residue Limits and Guideline Levels Proposed at 1978 Meeting. ANNEX 2 - References to Previous FAO and WHO Documentation. * Addendum to previously published monograph. 1978 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES AND ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE RESIDUES Rome 27 November - 6 December 1978 Members of the FAO Panel of Experts on Pesticide Residues and the Environment Dr. D.C. Abbott, Deputy Director (Customer Services), Laboratory of the Government Chemist, Cornwall House, Stamford Street, London SE1 9NQ, England, U.K. Mr. A. Ambrus, Department Head, Plant Protection and Agrochemistry Centre, H-1502 Budapest, P.O.B. 127, Hungary Dr. A.F.H. Besemer, Head, Pesticide Division, Plant Protection Service, 15 Geertjesweg, Wageningen, The Netherlands (Chairman) Dr. K.R. Hill, Chief, Analytical Chemistry Laboratory, U.S. Department of Agriculture, Agricultural Environmental Quality Institute, Room 114, Bld. 306, Beltssville, Maryland 20705, U.S.A. Dr. E.D. Magallona, Assistant Professor and Head, Pesticide Residue and Toxicology Laboratory, University of the Philippines at Los Baños, College, Languna 3720, Republic of the Philippines Mr. J.T. Snelson, Pesticides Co-ordinator, Department of Primary Industry, Canberra., A.C.T. 2600, Australia (Rapporteur) Observers Invited by FAO Dr. F-W. Kopisch-Obuch, German Agency for Technical Cooperation Ltd. (GTZ), Pesticide Residue Project D-6100 Darmstadt, Rheinstrasse 91, Postfach 4001, Federal Republic of Germany Mr. A.J. Pieters, Chairman, Codex Committee on Pesticide Residues, Public Health Inspector, Ministry of Public Health and Environmental Hygiene, Dokter Reijersstraat 12, Leidschendam, Netherlands Members of the WHO Expert Group on Pesticide Residues Dr. E.A. Bababunmi, Associate Professor (Reader), Department of Biochemistry, University of Ibadan, School of Medicine, Ibadan, Nigeria (Rapporteur) Mr. D.J. Clegg, Head, Pesticide Section, Toxicological Evaluation Division, Feeds Directorate, Health Protection Branch, Department of National Health and Welfare, Tunney's Pasture, Ottawa, K1A 0L2, Canada (Vice-Chairman) Prof. Dr. P. Engst, Central Institute for Nutrition, Academy of Sciences, (1505) Bergholz-Rehbrücke/DDR, German Democratic Republic Dr. S.D. Murphy, Professor of Toxicology, University of Texas Health Science Center at Houston, Medical School, P.O. Box 20708, Houston, Texas 77025, U.S.A. Dr. G.H. Sanai, Professor Department of Occupational and Environmental Health, School of Public Health, University of Teheran, P.O. Box 1310, Teheran, Iran Dr. B. Terracini, Professor of Cancer Epidemiology, University of Torino, Università di Torino, Via Santena 7, 10126 Torino, Italy Secretariat Dr. R.L. Baron, Health Effects Research Laboratory, Environmental Protection Agency Research Triangle Park, No. Carolina 27711, U.S.A. (Temporary Adviser) Mr. J.A.R. Bates, Ministry of Agriculture, Fisheries and Food, Plant Pathology Laboratory, Hatching Green, Harpenden, Herts. AL5 2BD, England Dr. L. Brader, Chief, Plant Protection Service, FAO, Rome, Italy Dr. C.L. Galli, Institute of Pharmacology and Pharmacognosy, School of Pharmacy, University of Milan, Via A. del Sarto 21, 20129 Milano, Italy (Temporary Adviser) Dr. A. Hassan, Technical Officer, Chemical Residue and Pollution Section, Joint FAO/IAEA. Division, P.O. Box 590, 1011 Vienna, Austria Dr. M. van Logten, Head, Laboratory for General Toxicology, National Institute of Public Health, Bilthoven, Netherlands (Temporary Adviser) Mr. A.F. Machin, Senior Research Officer, Central Veterinary Laboratory, Ministry of Agriculture Fisheries and Food, New Haw, Weybridge, Surrey KT15 3NB England, (Consultant) Dr. G. Schlatter, Professor of Toxicology, Institute of Toxicology, ETH and University of Zürich, CH-8603 Schwerzenbach (Zürich), Switzerland (Temporary Adviser) Dr. E.E. Turtle, Pesticides Specialist, Plant Protection Service, FAO, Rome, Italy (Joint Secretary) Dr. G. Vettorazzi, Scientist, Food Safety, Environmental Health Criteria and Standards, World Health Organization, Avenue Appia 1211, Geneva 27, Switzerland (Joint Secretary) INTRODUCTION The report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues and the Environment and the WHO Expert Group on Pesticide Residues held in Rome from 27 November to 6 December 1978 provides information on the general principles followed and the considerations of the meeting. It also contains a summary of the evaluations made on residues in foods of the various pesticides considered at the session. The present document contains summaries of the data considered at the session. The present document contains summaries of the data considered by the Meeting together with the recommendations made. As much relevant information as possible has been included in the monographs. This has been obtained from the published literature wherever possible, but other sources of information have also been used. Early and complete publications of the results of research in this field are very important, particularly of these parts which can form the basis for estimation of acceptable daily intakes and appropriate residue levels. Publication allows the research to be scrutinized and criticized by scientists from disciplines not necessarily represented at the meeting. Data contained in unpublished reports is less satisfactory and, when considered, must be complete and nonconfidential and indicate authorship. Some of the compounds considered at this meeting have been previously evaluated and reports on in earlier publications. If only a limited amount of additional information of these compounds has become available at this meeting, only this latter information is summarized in the pertinent monograph, and reference is made to the previously published evaluation, which should also be consulted by the reader who wishes to obtain a more complete evaluation of the compound. Such monograph addenda are indicated by an asterisk in the "Contents" sheet. Annex 1 to this volume of monographs gives a summary of the recommendations concerning acceptable daily intakes, residue limits and guideline levels made at the 1978 Meeting. It has already appeared as an Annex to the Report of the Meeting. NOTE TO THE READER Any comments on evaluation for acceptable daily intake should be addressed to: Food Safety Unit World Health Organization Geneva, Switzerland Any comments on residues in food and their evaluation should be addressed to: Plant Protection Service Plant Production and Protection Division Food and Agriculture Organization Rome, Italy
See Also: Toxicological Abbreviations