PESTICIDE RESIDUES IN FOOD - 1983
Sponsored jointly by FAO and WHO
EVALUATIONS 1983
Data and recommendations of the joint meeting
of the FAO Panel of Experts on Pesticide Residues
in Food and the Environment and the
WHO Expert Group on Pesticide Residues
Geneva, 5 - 14 December 1983
Food and Agriculture Organization of the United Nations
Rome 1985
The designations employed and the presentation of material in this
publication do not imply the expression of any opinion whatsoever on
the part of the Food and Agriculture Organization of the United
Nations concerning the legal status of any country, city or area or of
its authorities, or concerning the delimitation of its frontiers or
boundaries.
M-84
ISBN 92-5 102222-4
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Division, Food and Agriculture Organization of the United Nations, Via
delle Terme di Caracalla, 00100 Rome, Italy.
(c) FAO 1985
CONTENTS
List of Those Attending the Meeting
Introduction
The Monographs
Amitraz*
Residues
Azinphos-ethyl*
Residues
Azocyclotin
Residues
Benomyl*
Toxicology
Residues
Bitertanol
Toxicology
Bromide Ion
Residues
Butocarboxim
Residues
Carbendazim*
Toxicology
Residues
Carbophenothion*
Residues
Chinomethionat*
Residues
Chlorothalonil*
Toxicology
Residues
Chlorpyrifos*
Residues
Coumaphos*
Residues
Cyhexatin*
Residue
Cypermethrin*
Residues
Daminozide*
Toxicology
Dichlofluanid*
Toxicology
Residues
Diflubenzuron*
Residues
Dimethoate*
Residues
Dithiocarbamates*
Residues
Ethephon*
Residues
Ethiofencarb*
Residues
Ethion*
Residues
Ethoprophos
Toxicology
Fenchlorphos*
Residues
Fenitrothion*
Residues
Fensulfothion*
Residues
Fenthion*
Residues
Mecarbam*
Toxicology
Residues
Methiocarb*
Toxicology
Residues
Nitrofen
Toxicology
Residues
Oxamyl*
Residues
Permethrin*
Residues
Phoxim
Residues
Pirimiphos-methyl*
Residues
Prochloraz
Toxicology
Residues
Propoxur*
Residues
Triadimefon*
Toxicology
Residues
Triazophos*
Residues
Annex I - Acceptable daily intakes, maximum residue limits and
guideline levels proposed at the 1983 Meeting
Annex II - Previous FAO and WHO Documentation
* Addendum
1983 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES
IN FOOD AND THE ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE
RESIDUES
Geneva, 5-14 December 1983
FAO Panel of Experts on Pesticide Residues in Food and the
Environment
A. Ambrus, Plant Protection and Agrochemistry Centre, Budapest,
Hungary
J.A.R. Bates, Pesticide Registration Department, Ministry of
Agriculture, Fisheries and Food, Hatching Green, Harpenden,
Herts, UK(Rapporteur)
K.R. Hill, Chemistry Laboratory, US Department of Agriculture,
Agricultural Environment Quality Institute, Beltsville, Md, USA
(Chairman)
N.F. Ives, Office of Pesticide Programs, Environmental Protection
Agency, Washington DC, USA
J.T. Snelson, Department of Primary Industry, Canberra, Australia
Vice-Chairman)
Voldum-Clausen, Division of Pesticides and Contaminants, National Food
Institute, Soborg, Denmark
Observer invited by FAO
A.J. Pieters, Directorate of Public Health, Foodstuffs Division,
Leidschendam, The Netherlands (Chairman of the Codex Committee on
Pesticide Residues)
WHO Expert Group on Pesticide Residues
V. Benes, Department of Toxicology, Institute of Hygiene and
Epidemiology, Prague, Czechoslovakia
D. Clegg, Pesticide Section, Toxicological Evaluation Division, Food
Directorate, Health Protection Branch, Ottawa, Canada (Chairman)
S. Jetanasen*, Epidemiology Division, Office of the Under-Secretary,
Ministry of Public Health, Bangkok, Thailand
M. Lotti, Istituto di Medicina del Lavoro, Padua, Italy (Rapporteur)
D. de Paola, Department of Pathology, School of Medicine, Federal
University, Rio de Janeiro, Brazil
O.E. Paynter, Hazard Evaluation Division, US Environmental Protection
Agency, Washington DC, USA
FAO/WHO Secretariat
A. L. Black, Commonwealth Department of Health, Woden, Australia (WHO
Temporary Adviser)
J.R. Cabral, Unit of Mechanisms of Carcinogenesis, International
Agency for Research on Cancer, Lyon, France
A. di Muccio, Toxicological Laboratory - Pesticide Section, Instituto
Superiore di Sanita, Rome, Italy (WHO Temporary Adviser)
R. B. Jaeger, Toxicology Branch, Hazard Evaluation Division, US
Environmental Protection Agency, Washington DC, USA (WHO
Temporary Adviser)
F-W. Kopisch-Obuch, Plant Protection Service, FAO, Rome, Italy
(Secretary of FAO Panel of Experts on Pesticide Residues in Food
and the Environment)
L. G Ladomery, Joint FAO/WHO Food Standards Programme, FAO, Rome,
Italy
A.F. Machin, Ministry of Agriculture, Fisheries and Food, Central
Veterinary Laboratory, Weybridge, Surrey, UK (FAO Consultant)
T. Pekkanen, Department of Food Hygiene, College of Veterinary
Medicine, Helsinki, Finland (WHO Temporary Adviser)
M. Repetto*, Regional Toxicology Institute, Seville, Spain (WHO
Temporary Adviser)
M. Tobe, Toxicological Division, National Institute of Hygienic
Sciences, Tokyo, Japan (WHO Temporary Adviser)
G. Vettorazzi, International Programme on Chemical Safety, Division of
Environmental Health, WHO, Geneva, Switzerland (Secretary of the
WHO Export Group on Pesticide Residues)
E. Weisenberg, Institute for the Standardization and Control of
Pharmaceuticals, Ministry of Health, Jerusalem, Israel (WHO
Temporary Adviser)
D.L. Wu-Lau*, Pesticides Section, Toxicology Evaluation Division, Food
Directorate, Health Protection Branch, Ottawa, Canada (WHO
Temporary Adviser
Additional WHO Temporary Advisers**
E.R. Budd, Office of Pesticide Programs, US Environmental Protection
Agency, Washington DC, USA
N. Ito, First Department of Pathology, Nagoya City University, Medical
School, Nagoya, Japan
P. Shubik, Green College at the Radcliffe Observatory, Oxford OX2
6HG,UK
* Invited but unable to attend
** Present only at the discussion of o-phenylphenol and its sodium
salt
INTRODUCTION
The report of the Joint Meeting of the FAO Panel of Experts on
Pesticide Residues in Food and the Environment and the WHO Expert
Group on Pesticide Residues, held in Rome from 24 September to
3 October 1984 contains a summary of the evaluations of residues in
foods of the various pesticides considered at the session as well as
information on the general principles followed by the Meeting. The
present document contains summaries of the data considered, together
with the recommendations made.
The information included in the monographs has been obtained from
the published literature wherever possible, but other sources have
also been included. Early and complete publication of the results of
research in this field are very important, particularly those data
which can form the basis for the estimation of acceptable daily
intakes and appropriate residue levels. Publication allows the
research to be assessed by scientists from disciplines not necessarily
represented at the meeting. Data contained in unpublished reports are
less satisfactory and, when considered, must be complete and
nonconfidential and indicate authorship.
Some of the compounds considered At this Meeting have been
previously evaluated and reported on in earlier publications. Only new
information is summarized in the relevant monographs and reference is
made to the previously published evaluation(s), which should also be
consulted. Such monograph addenda are indicated by an asterisk in the
"Contents" sheet.
Annex 1 to this volume of monographs summarizes the
recommendations on acceptable daily intakes, maximum residue limits
and guideline levels made at the 1984 Meeting. It has already appeared
as an annex to the report of the Meeting.
NOTE
Any comments on evaluation for acceptable daily intake should be
addressed to:
Food Safety Unit
World Health Organization
Geneva, Switzerland
Any comments on residues in food and their evaluation should be
addressed to:
Pesticide Residues Specialist
Plant Protection Service
Plant Production and Protection Division
Food and Agriculture Organization
Rome, Italy