PESTICIDE RESIDUES IN FOOD - 1983 Sponsored jointly by FAO and WHO EVALUATIONS 1983 Data and recommendations of the joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues Geneva, 5 - 14 December 1983 Food and Agriculture Organization of the United Nations Rome 1985 The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations concerning the legal status of any country, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. M-84 ISBN 92-5 102222-4 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise, without the prior permission of the copyright owner. Applications for such permission, with a statement of the purpose and extent of the reproduction, should be addressed to the Director, Publications Division, Food and Agriculture Organization of the United Nations, Via delle Terme di Caracalla, 00100 Rome, Italy. (c) FAO 1985 CONTENTS List of Those Attending the Meeting Introduction The Monographs Amitraz* Residues Azinphos-ethyl* Residues Azocyclotin Residues Benomyl* Toxicology Residues Bitertanol Toxicology Bromide Ion Residues Butocarboxim Residues Carbendazim* Toxicology Residues Carbophenothion* Residues Chinomethionat* Residues Chlorothalonil* Toxicology Residues Chlorpyrifos* Residues Coumaphos* Residues Cyhexatin* Residue Cypermethrin* Residues Daminozide* Toxicology Dichlofluanid* Toxicology Residues Diflubenzuron* Residues Dimethoate* Residues Dithiocarbamates* Residues Ethephon* Residues Ethiofencarb* Residues Ethion* Residues Ethoprophos Toxicology Fenchlorphos* Residues Fenitrothion* Residues Fensulfothion* Residues Fenthion* Residues Mecarbam* Toxicology Residues Methiocarb* Toxicology Residues Nitrofen Toxicology Residues Oxamyl* Residues Permethrin* Residues Phoxim Residues Pirimiphos-methyl* Residues Prochloraz Toxicology Residues Propoxur* Residues Triadimefon* Toxicology Residues Triazophos* Residues Annex I - Acceptable daily intakes, maximum residue limits and guideline levels proposed at the 1983 Meeting Annex II - Previous FAO and WHO Documentation * Addendum 1983 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES IN FOOD AND THE ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE RESIDUES Geneva, 5-14 December 1983 FAO Panel of Experts on Pesticide Residues in Food and the Environment A. Ambrus, Plant Protection and Agrochemistry Centre, Budapest, Hungary J.A.R. Bates, Pesticide Registration Department, Ministry of Agriculture, Fisheries and Food, Hatching Green, Harpenden, Herts, UK(Rapporteur) K.R. Hill, Chemistry Laboratory, US Department of Agriculture, Agricultural Environment Quality Institute, Beltsville, Md, USA (Chairman) N.F. Ives, Office of Pesticide Programs, Environmental Protection Agency, Washington DC, USA J.T. Snelson, Department of Primary Industry, Canberra, Australia Vice-Chairman) Voldum-Clausen, Division of Pesticides and Contaminants, National Food Institute, Soborg, Denmark Observer invited by FAO A.J. Pieters, Directorate of Public Health, Foodstuffs Division, Leidschendam, The Netherlands (Chairman of the Codex Committee on Pesticide Residues) WHO Expert Group on Pesticide Residues V. Benes, Department of Toxicology, Institute of Hygiene and Epidemiology, Prague, Czechoslovakia D. Clegg, Pesticide Section, Toxicological Evaluation Division, Food Directorate, Health Protection Branch, Ottawa, Canada (Chairman) S. Jetanasen*, Epidemiology Division, Office of the Under-Secretary, Ministry of Public Health, Bangkok, Thailand M. Lotti, Istituto di Medicina del Lavoro, Padua, Italy (Rapporteur) D. de Paola, Department of Pathology, School of Medicine, Federal University, Rio de Janeiro, Brazil O.E. Paynter, Hazard Evaluation Division, US Environmental Protection Agency, Washington DC, USA FAO/WHO Secretariat A. L. Black, Commonwealth Department of Health, Woden, Australia (WHO Temporary Adviser) J.R. Cabral, Unit of Mechanisms of Carcinogenesis, International Agency for Research on Cancer, Lyon, France A. di Muccio, Toxicological Laboratory - Pesticide Section, Instituto Superiore di Sanita, Rome, Italy (WHO Temporary Adviser) R. B. Jaeger, Toxicology Branch, Hazard Evaluation Division, US Environmental Protection Agency, Washington DC, USA (WHO Temporary Adviser) F-W. Kopisch-Obuch, Plant Protection Service, FAO, Rome, Italy (Secretary of FAO Panel of Experts on Pesticide Residues in Food and the Environment) L. G Ladomery, Joint FAO/WHO Food Standards Programme, FAO, Rome, Italy A.F. Machin, Ministry of Agriculture, Fisheries and Food, Central Veterinary Laboratory, Weybridge, Surrey, UK (FAO Consultant) T. Pekkanen, Department of Food Hygiene, College of Veterinary Medicine, Helsinki, Finland (WHO Temporary Adviser) M. Repetto*, Regional Toxicology Institute, Seville, Spain (WHO Temporary Adviser) M. Tobe, Toxicological Division, National Institute of Hygienic Sciences, Tokyo, Japan (WHO Temporary Adviser) G. Vettorazzi, International Programme on Chemical Safety, Division of Environmental Health, WHO, Geneva, Switzerland (Secretary of the WHO Export Group on Pesticide Residues) E. Weisenberg, Institute for the Standardization and Control of Pharmaceuticals, Ministry of Health, Jerusalem, Israel (WHO Temporary Adviser) D.L. Wu-Lau*, Pesticides Section, Toxicology Evaluation Division, Food Directorate, Health Protection Branch, Ottawa, Canada (WHO Temporary Adviser Additional WHO Temporary Advisers** E.R. Budd, Office of Pesticide Programs, US Environmental Protection Agency, Washington DC, USA N. Ito, First Department of Pathology, Nagoya City University, Medical School, Nagoya, Japan P. Shubik, Green College at the Radcliffe Observatory, Oxford OX2 6HG,UK * Invited but unable to attend ** Present only at the discussion of o-phenylphenol and its sodium salt INTRODUCTION The report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues, held in Rome from 24 September to 3 October 1984 contains a summary of the evaluations of residues in foods of the various pesticides considered at the session as well as information on the general principles followed by the Meeting. The present document contains summaries of the data considered, together with the recommendations made. The information included in the monographs has been obtained from the published literature wherever possible, but other sources have also been included. Early and complete publication of the results of research in this field are very important, particularly those data which can form the basis for the estimation of acceptable daily intakes and appropriate residue levels. Publication allows the research to be assessed by scientists from disciplines not necessarily represented at the meeting. Data contained in unpublished reports are less satisfactory and, when considered, must be complete and nonconfidential and indicate authorship. Some of the compounds considered At this Meeting have been previously evaluated and reported on in earlier publications. Only new information is summarized in the relevant monographs and reference is made to the previously published evaluation(s), which should also be consulted. Such monograph addenda are indicated by an asterisk in the "Contents" sheet. Annex 1 to this volume of monographs summarizes the recommendations on acceptable daily intakes, maximum residue limits and guideline levels made at the 1984 Meeting. It has already appeared as an annex to the report of the Meeting. NOTE Any comments on evaluation for acceptable daily intake should be addressed to: Food Safety Unit World Health Organization Geneva, Switzerland Any comments on residues in food and their evaluation should be addressed to: Pesticide Residues Specialist Plant Protection Service Plant Production and Protection Division Food and Agriculture Organization Rome, Italy
See Also: Toxicological Abbreviations