PESTICIDE RESIDUES IN FOOD - 1980 Sponsored jointly by FAO and WHO EVALUATIONS 1980 Joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues Rome, 6-15 October 1980 The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. M-84 ISBN 92-5-101148-6 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise, without the prior permission of the copyright owner. Applications for such permission, with a statement of the purpose and extent of the reproduction, should be addressed to the Director, Publications Division, Food and Agriculture Organization of the United Nations, Via delle Terme di Caracalla, 00100 Rome, Italy. (c) FAO 1981 This document contains summaries of the data considered by the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues, which met in Rome, 6 to 15 October 1980, together with the recommendations made. A report of the 1980 Joint Meeting, which outlines the principles on which the evaluations were carried out and summarises the recommendations made, has also been published.* * Pesticide Residues in Food: Report of the 1980 Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues, FAO Plant Production and Protection Series No. 26, 1981. Previous FAO and WHO documentation is listed in Annex II. CONTENTS List of Attendees Introduction The Monographs Amitraz sec-Butylamine* Captan* Carbofuran* Carbophenothion* Chlordimeform Chlorobenzilate* Coumaphos* Cyanofenphos* Cyhexatin* 2,4 - D* DDT* Deltamethrin Dithiocarbamates* Ethiofencarb* Etrimfos Fenamiphos* Fenthion* Guazatine* Imazalil* Iprodione* Maleic Hydrazide* Mecarbam Methacrifos Omethoate* Oxamyl Parathion-Methyl* Permethrin* Phenothrin Phenthoate Propargite* Compounds marked * have been evaluated previously. Annex I Annex II 1980 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES IN FOOD AND THE ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE RESIDUES Rome, 6 - 15 October 1980 FAO Panel of Experts on Pesticide Residues in Food and The Environment Dr. D.C. Abbott, Deputy Director (Customer Services), Laboratory of the Government Chemist, Cornwall House, Stamford Street, London SE1 9NQ, U.K. Dr. A. Ambrus, Department Head, Analytical Department, Plant Protection and Agrochemistry Centre, H-1502 Budapest, P.O.B. 127, Hungary. Prof. Dr. A.F.H. Besemer, Head, Pesticides Division, Plant Protection Service, Geertjesweg 15, 6706 EA Wageningen, Netherlands. Prof. Dr. G. Bressau, Chief, Pesticides Residues Unit, Pesticides Department, Federal Health Office, Bundesgesundheitsamt, Postfach 330013, D-1000 Berlin 33. Dr. K.R. Hill, Chief, Analytical Chemistry Laboratory, U.S. Department of Agriculture, SEA/AR, Agricultural Environmental Quality Institute -ACL, Beltsville, Maryland 20705, U.S.A. Mr. N.F. Ives, Chemist, U.S. Environmental Protection Agency, Office of Pesticide Programs, Hazard Evaluation Division TS-769, CM No. 2, 1921 Jefferson Davis Highway, Arlington, Virginia 22202, U.S.A. Dr. E.M. Thain, Deputy Director, Tropical Products Institute, 56/62 Grays Inn Road, London WC1X 8LU, U.K. Observers Invited by FAO Mr. C.W. Collier, Pest Management Specialist, U.S. Agency for International Development DS/AGR, RPC 413C, Washington, D.C. 20530, U.S.A. Ir. A.J. Pieters, Directorate of Public Health, Foodstuffs Division, Dokter Reijersstraat 12, Leidschendam, Netherlands (Chairman of Codex Committee on Pesticide Residues). WHO Expert Group on Pesticide Residues Prof. C. Amerasekera, Head, Department of Forensic Medicine, University of Peradeniya, Sri Lanka. Prof. E. Astolfi, Professor of Toxicology, Facultad de Medicina, Universidad de Buenos Aires, Ajacucho 1337, Buenos Aires (1111), Argentina. Dr. I. Nir-Grosfeld, Hebrew University, Herdanah Medical School, Jerusalem, Israel. Prof. D.V.W. Parke, Head, Department of Biochemistry, University of Surrey, Guildford, Surrey, U.K. Dr. O.E. Paynter, U.S. Department of Commerce, Office of Environmental Affairs, Washington, D.C., U.S.A. Prof. A. Somogyi, Director, Department of Drugs, Animal Nutrition and Residue Research, Bundesgesundheitsamt, Thielallee 88-92, D-1000 Berlin 33. FAO/WHO Secretariat Dr. R.L. Baron, Health Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina 27711, U.S.A. (WHO Temporary Adviser). Mr. J.A.R. Bates, Pesticide Residues Specialist, Plant Protection Service, FAO, 00100 Rome, Italy (Secretary of FAO Panel of Experts on Pesticide Residues in Food and the Environment). Dr. J. Cabral, Unit of Chemical Carcinogenesis, International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 2, France (WHO Temporary Adviser). Mr. A.F. Machin, Senior Research Officer, Central Veterinary Laboratory, Ministry of Agriculture, Fisheries and Food, New Haw, Weybridge, Surrey KT15 3NB, U.K. (FAO Consultant). Dr. M. van Logten, National Institute of Public Health, Bilthoven, Netherlands (WHO Temporary Adviser). Dr. G. Vettorazzi, Toxicologist - Food, International Programs on Chemical Safety, Division of Environmental Health, WHO, 1211 Geneva 27, Switzerland (Secretary of WHO Expert Group on Pesticide Residues). Others Attending Dr. L. Ladomery, Food Standards Officer, Joint FAO/WHO Food Standards Programme, FAO, Rome, Italy (Secretary of Codex Committee on Pesticide Residues). Mr. J. Wessel, International Programme on Chemical Safety, Division of Environmental Health, WHO, 1211 Geneva 27, Switzerland (WHO Temporary Adviser). Monographs edited by Mr. D.F. Lee and Dr. N.A. Smart (FAO Consultants) INTRODUCTION The report of the joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues held in Rome from 6 to 15 October 1980, contains a summary of the evaluations of residues in foods of the various pesticides considered at the session as well as information on the general principles followed by the meeting. The present document contains summaries of the data considered, together with the recommendations made. The information included in the monographs has been obtained from the published literature wherever possible, but other sources have also been used. Early and complete publications of the results of research in this field are very important, particularly those data which can form the basis for the estimation of acceptable daily intakes and appropriate residue levels. Publication allows the research to be assessed by scientists from disciplines not necessarily represented at the meeting. Data contained in unpublished reports is less satisfactory and, when considered, must be complete and nonconfidential and indicate authorship. Some of the compounds considered at this meeting have been previously evaluated and reported on in earlier publications. Only new information is summarized in the relevant monographs and reference is made to the previously published evaluation(s) which should also be consulted. Such monograph addenda are indicated by an asterisk in the "Contents" sheet. Annex 1 to this volume of monographs summarizes the recommendations on acceptable daily intakes, maximum residue limits and guideline levels made at the 1980 meeting. It has already appeared as an annex to the report of the meeting. NOTE Any comments on evaluation for acceptable daily intake should be addressed to: Food Safety Unit World Health Organization Geneva, Switzerland Any comments on residues in food and their evaluation should be addressed to: Pesticide Residues Specialist Plant Protection Service Plant Production and Protection Division Food and Agriculture Organization Rome, Italy
See Also: Toxicological Abbreviations