PESTICIDE RESIDUES IN FOOD - 1982 Sponsored jointly by FAO and WHO EVALUATIONS 1982 Data and recommendations of the joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues Rome, 23 November - 2 December 1982 Food and Agriculture Organization of the United Nations Rome 1983 The designations employed and the presentation of material in this publication do not imply the expression of any opinion whatsoever on the part of the Food and Agriculture Organization of the United Nations concerning the legal status of any country, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. M-84 ISBN 92-5 101432-9 All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying or otherwise, without the prior permission of the copyright owner. Applications for such permission, with a statement of the purpose and extent of the reproduction, should be addressed to the Director, Publications Division, Food and Agriculture Organization of the United Nations, Via delle Terme di Caracalla, 00100 Rome, Italy. (c) FAO 1983 CONTENTS List of Those Attending the Meeting Introduction The Monographs Acephate* WHO - Toxicology Aldicarb* WHO - Toxicology FAO - Residues Azocyclotin/Cyhexatin* FAO - Residues Bendiocarb WHO - Toxicology FAO - Residues Bromophos* FAO - Residues Captan* WHO - Toxicology Chlordane* WHO - Toxicology Chlorpyrifos* WHO - Toxicology FAO - Residues Cyanofenphos* FAO - Residues Cypermethrin* FAO - Residues Deltamethrin* WHO - Toxicology FAO - Residues Dichlofluanid* FAO - Residues * Addendum Diphenylamine* WHO - Toxicology Endosulfan* WHO - Toxicology Ethiofencarb* WHO - Toxicology FAO - Residues Ethion* WHO - Toxicology Etrimfos* WHO - Toxicology Fenitrothion* WHO - Toxicology Fensulfothion* WHO - Toxicology Isofenphos* WHO - Toxicology FAO - Residues Metalaxyl WHO - Toxicology FAO - Residues Methacrifos* WHO - Toxicology Methamidophos* WHO - Toxicology Paraquat* WHO - Toxicology Parathion Methyl* WHO - Toxicology Permethrin* FAO - Residues Phorate* WHO - Toxicology * Addendum Phosphamidon* WHO - Toxicology Phoxim WHO - Toxicology Pirimicarb* WHO - Toxicology Propargite* WHO - Toxicology FAO - Residues Triazophos WHO - Toxicology Vamidothion* WHO - Toxicology Annex I - Acceptable Daily Intakes, Maximum Residue Limits and Guideline Levels Proposed at the 1982 Meeting Annex II - Previous FAO and WHO Documentation * Addendum 1982 JOINT MEETING OF THE FAO PANEL OF EXPERTS ON PESTICIDE RESIDUES IN FOOD AND THE ENVIRONMENT AND THE WHO EXPERT GROUP ON PESTICIDE RESIDUES Rome, 22 November - 1 December 1982 FAO Panel of Experts on Pesticide Residues in Food and the Environment A. Ambrus, Plant Protection and Agrochemistry Centre, Budapest, Hungary J.A.R. Bates, Pesticide Registration Department, Ministry of Agriculture, Fisheries and Food, Hatching Green, Harpenden, Herts, UK (Rapporteur) K.R. Hill, Analytical Chemistry Laboratory, US Department of Agriculture, Agricultural Environment Quality Institute, Beltsville, Md, USA (Chairman) N.F. Ives, Office of Pesticide Programs, Environmental Protection Agency, Washington, DC, USA M.A. Martinez, Department of Pesticides, Dirección/General, Sanidad Vegetal, Mexico City, Mexico K. Voldum-Clausen, Division of Pesticides and Contaminants, National Food Institute, Soborg, Denmark Observer invited by FAO A.J. Pieters, Directorate of Public Health, Foodstuffs Division, Leidschendam, Netherlands (Chairman of the Codex Committee on Pesticide Residues) WHO Expert Group on Pesticide Residues C. Amerasekere, Department of Forensic Medicine, University of Peradeniya, Peradeniya, Sri Lanka D. Clegg, Pesticide Section, Toxicological Evaluation Division, National Health and Welfare, Ottawa, Canada (Vice-Chairman) D. de Paola, Department of Pathology, University Hospital, Rio de Janeiro, Brazil D.V. Parke, Department of Biochemistry, University of Surrey, Guildford, England O.E. Paynter, US Department of Commerce, Washington, DC, USA R. Plestina, Institute for Medical Research and Occupational Health, Zagreb, Yugoslavia FAO/WHO Secretariat A. Adam, Plant Protection Service, FAO, Rome, Italy (Secretary of the FAO Panel of Experts on Pesticide Residues in Food and the Environment) A.L. Black, Commonwealth Department of Health, Woden, Australia (WHO Temporary Adviser) J.R. Cabral, Unit of Chemical Carcinogenesis, International Agency for Research on Cancer, Lyon, France A. Di Muccio, Toxicological Laboratory, Instituto Superiore de Sanità, Rome, Italy (WHO Temporary Adviser) R.B. Jaeger, US Environmental Protection Agency, Washington, DC, USA (WHO Temporary Adviser) A.F. Machin, Central Veterinary Laboratory, Ministry of Agriculture, Fisheries and Food, Weybridge, Surrey, UK (FAO Consultant) T. Pekkanen, Department of Food Hygiene, College of Veterinary Medicine, Helsinki, Finland (WHO Temporary Adviser) R. Read, International Programme on Chemical Safety, Division of Environmental Health, WHO, Geneva, Switzerland A.G. Rico, Laboratoire de Radioélements et d'Etudes Métaboliques, Ecole Nationale Vétérinaire, Toulouse, France (WHO Temporary Adviser) M. Tobe, Division of Toxicology, Biological Research Centre, National Institute of Hygienic Sciences, Tokyo, Japan (WHO Temporary Adviser) G. Vettorazzi, International Programme on Chemical Safety, Division of Environmental Health, WHO, Geneva, Switzerland (Secretary of the WHO Expert Group on Pesticide Residues) E. Weisenberg, Institute for the Standardization and Control of Pharmaceuticals, Ministry of Health, Jerusalem, Israel (WHO Temporary Adviser) D. Wu-Lau, Pesticide Section, National Health and Welfare, Ottawa, Canada, (WHO Temporary Adviser) K. Zammarano, Plant Protection Service, FAO, Rome, Italy (Monographs Editor) INTRODUCTION The report of the Joint Meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Expert Group on Pesticide Residues, held in Rome from 22 November - 1 December 1982, contains a summary of the evaluations of residues in foods of the various pesticides considered at the session as well as information on the general principles followed by the Meeting. The present document contains summaries of the data considered, together with the recommendations made. The information included in the monographs has been obtained from the published literature wherever possible, but other sources have also been used. Early and complete publication of the results of research in this field are very important, particularly those data which can form the basis for the estimation of acceptable daily intakes and appropriate residue levels. Publication allows the research to be assessed by scientists from disciplines not necessarily represented at the meeting. Data contained in unpublished reports is less satisfactory and, when considered, must be complete and nonconfidential and indicate authorship. Some of the compounds considered at this Meeting have been previously evaluated and reported on in earlier publications. Only new information is summarized in the relevant monographs and reference is made to the previously published evaluation(s), which should also be consulted. Such monograph addenda are indicated by an asterisk in the "Contents" sheet. Annex 1 to this volume of monographs summarizes the recommendations on acceptable daily intakes, maximum residue limits and guideline levels made at the 1982 Meeting. It has already appeared as an annex to the report of the Meeting. NOTE Any comments on evaluation for acceptable daily intake should be addressed to: Food Safety Unit World Health Organization Geneva, Switzerland Any comments on residues in food and their evaluation should be addressed to: Pesticide Residues Specialist Plant Protection Service Plant Production and Protection Division Food and Agriculture Organization Rome, Italy
See Also: Toxicological Abbreviations